📄 Category

health economics

34 papers

Economic value of resistance-guided gonorrhea treatment: cost-neutrality thresholds for resistance test pricing in the United States

This study uses a stochastic simulation model to demonstrate that resistance-guided gonorrhea treatment in the United States offers significant economic value across multiple dimensions, with cost-neutrality thresholds for diagnostic tests ranging from near zero to $145 depending on resistance prevalence and the inclusion of system-level costs like delayed resistance emergence and avoided drug development.

Nichols, B. E., Wonderly Trainor, B., Hampson, G. + 2 more2026-04-07📄 health economics

Updated Health Opportunity Cost Estimates for 92 Low- and Middle-Income Countries: Implications for Global Health Financing and Donor Allocation

This paper presents updated marginal cost estimates per disability-adjusted life year (DALY) averted for 92 low- and middle-income countries using recent data and previously established elasticities, demonstrating that aligning domestic health spending with the Abuja Declaration and reallocating development assistance based on these opportunity costs could significantly maximize global health gains.

Ochalek, J. M.2026-04-02📄 health economics

Defining the potential impact and cost-effectiveness of a non-invasive diagnostic for malaria: a modeling study

This modeling study demonstrates that while universal non-invasive diagnostics (NIDs) maximize malaria case detection, a hybrid strategy combining NID screening with confirmatory rapid diagnostic tests offers the optimal balance of improved case finding, reduced antimicrobial overuse, and cost-effectiveness across diverse epidemiological settings.

Hansen, M. A., de Nooy, A., Calarco, S. + 2 more2026-04-01📄 health economics

Magnitude and Associated Factors of Out-of-Pocket Healthcare Expenditure among Outpatients Visiting Public Hospitals in Jigjiga Town, Somali Region, Eastern Ethiopia

This study reveals that out-of-pocket healthcare expenditure is highly prevalent among outpatients in Jigjiga, Ethiopia, with nearly 90% of patients incurring costs, and identifies female sex, unmarried status, higher education, and longer travel distances as significant predictors of these expenses.

Ahmed, M. M., Shitaye, D. D., Cheru, A. + 2 more2026-03-30📄 health economics

Determining context-specific economically feasible age ranges for female HPV catch-up vaccination in LMICs: a model-based health economic assessment

This model-based assessment of 132 low- and middle-income countries demonstrates that expanding female HPV catch-up vaccination up to age 30 is highly impactful and cost-effective for cervical cancer elimination, though its budgetary feasibility varies significantly and relies heavily on sustainable financing and Gavi support.

Wondimu, A., Georges, D., Macacu, A. + 5 more2026-03-27📄 health economics

The State of Health Visiting in England: Workforce Composition, Caseloads and Service Delivery

Utilizing new Freedom of Information data from 147 English Local Authorities, this study reveals that while health visiting spending remains progressive and mandated contact completion is stable across deprivation levels, the workforce has contracted and shifted toward lower-skilled staff with rising caseload pressures that disproportionately affect the most deprived areas, necessitating approximately 3,100 additional staff and £120 million annually to restore recommended service levels.

Conti, G., Weber Costa, G., D'Mello, D. + 1 more2026-03-27📄 health economics

A Smart Investment: The Health, Education, and Economic Returns of Malaria Chemoprevention in School-Aged Children Across Ten High-Burden Countries

This study demonstrates that malaria chemoprevention for school-aged children across ten high-burden sub-Saharan African countries is a highly cost-effective investment, generating substantial societal net benefits through improved health, reduced school absenteeism, and enhanced educational outcomes, with benefit-cost ratios ranging from 3.71 to 39.5.

Snyman, K., Angrist, N., Cohee, L. M. + 1 more2026-03-25📄 health economics

Does the Health System Model Shape Prevention? Evidence from 22 OECD Countries (2004-2023)

This study analyzing 22 OECD countries from 2004 to 2023 finds that the share of health expenditure allocated to prevention is largely independent of a healthcare system's structural organization (financing and provision), suggesting that investment in prevention is driven more by external political and strategic factors than by the system's inherent design.

Marraffa, P., Marega, L., Politano, G. + 1 more2026-03-23📄 health economics

Building a Resilient Antibiotic Market: India Sets the Pace An econometric modelling approach to estimate revenues in Indian private markets for a novel, broad-spectrum intravenous antibiotic

This paper employs econometric modeling to demonstrate that India, facing a severe antibiotic resistance crisis, can pioneer the market entry and financial viability of novel broad-spectrum intravenous antibiotics through innovative revenue strategies, thereby transforming the country into a global hub for antibiotic innovation and health security.

Maitreyi, L., Rajagopal, S., Anandkumar, A. + 1 more2026-03-22📄 health economics

The Economic Burden of KCNT1-Related Disorders in the United States: Insights from Caregiver-Reported and EMR-Derived Data

This study quantifies the substantial economic burden of KCNT1-related disorders in the United States by combining caregiver-reported and electronic medical record data, revealing that annual costs per family range from approximately $355,000 to nearly $800,000 and are driven primarily by hospitalizations and caregiving-related income loss, thereby underscoring the urgent need for targeted therapies and systemic policy support.

Abuhl, A., Bryan, B. A., Wright, M. + 3 more2026-03-17📄 health economics

Cost-effectiveness of end-game strategies against sleeping sickness across the Democratic Republic of Congo

This study models the cost-effectiveness of various end-game strategies in the Democratic Republic of Congo, finding that while front-loaded investments are required to achieve elimination of transmission by 2030 in most health zones, such ambitious efforts would significantly reduce mortality and prove cost-effective compared to the status quo.

Antillon, M., Huang, C.-I., Sutherland, S. A. + 14 more2026-03-16📄 health economics

Bayesian Joint Longitudinal-Survival Modeling of Functional Recovery Trajectories and Time to Independent Community Ambulation Following Robotic Exoskeleton-Assisted Stroke Rehabilitation: A Multi-Centre Cohort Study in Canada

This multi-centre Canadian cohort study utilized a Bayesian joint modelling framework to demonstrate that both the current level and the rate of improvement in lower-extremity motor function are independently predictive of achieving independent community ambulation following robotic exoskeleton-assisted stroke rehabilitation, thereby supporting dynamic, trajectory-based treatment planning.

Lim, A., Desai, P.2026-03-16📄 health economics

Resource need and cost estimates for universal health coverage across 122 countries using the WHO UHC Compendium

This study utilizes a new ingredient-based costing model aligned with the WHO UHC Compendium to estimate that achieving 80% coverage of essential health interventions across 122 low- and middle-income countries would require an annual investment of USD 2.0 trillion, providing a transparent and practical framework for national health planning.

Nederpelt, C., Abou Jaoude, G., Surgey, G. + 5 more2026-03-13📄 health economics

Opportunities for cost reduction of current first-line WHO-recommended oral antiretroviral therapy: replacing tenofovir disoproxil fumarate with tenofovir alafenamide

Replacing tenofovir disoproxil fumarate with tenofovir alafenamide in South Africa's first-line HIV treatment regimen could reduce annual program costs by approximately 5% (around US$54 million) while maintaining clinical effectiveness, offering a feasible interim cost-saving strategy amidst declining funding.

Jamieson, L., Venter, W. D. F., Meyer-Rath, G.2026-03-13📄 health economics

Threshold Effects of Rehabilitation Intensity on Functional Recovery After Ischaemic Stroke: A Panel Threshold Regression Analysis of Australian Hospital Data

This study of 18,742 Australian stroke patients reveals a non-linear relationship between rehabilitation intensity and functional recovery, identifying a critical "sweet spot" of 27.4 to 54.7 minutes of daily therapy where functional gains are maximized, while lower intensities yield suboptimal results and higher intensities encounter diminishing returns.

Lim, A., Venkataraman, P.2026-03-12📄 health economics