Brain-Controlled Epidural Stimulation Reveals Enhanced Corticospinal Excitability and Upper-Limb Function in Chronic Tetraplegia

This first-in-human case study demonstrates that pairing an implantable brain-computer interface with cervical epidural spinal cord stimulation to deliver intention-driven neuromodulation induces corticospinal plasticity and yields immediate, sustained improvements in upper-limb motor function for an individual with chronic, motor-complete tetraplegia.

Sasaki, A., Fadli, R. A., Yuasa, A. + 21 more2026-04-06📄 rehabilitation medicine and physical therapy

Biologically informed geometry and force distribution improve task performance in agonist/antagonist tendon-driven prosthetic hands

The study demonstrates that the HAMR framework, which generates customized agonist/antagonist tendon-driven prosthetic hands based on individual morphology and functional needs, significantly improves task performance and reduces user burden compared to designs with generalized anthropomorphic geometry, particularly for gross motor activities.

Velasquez, L. I., Brown, J. D.2026-04-06📄 rehabilitation medicine and physical therapy

Patient characteristics associated with participation in cardiorespiratory exercise during stroke rehabilitation: a multisite observational cohort study

This multisite observational cohort study found that only 40.1% of stroke rehabilitation patients participated in cardiorespiratory exercise, with participation significantly hindered by cardiac and mental health conditions or severe mobility limitations, and even among those who exercised, merely 1.5% met recommended intensity and duration guidelines.

Devasahayam, A. J., Tang, A., Zhong, Y. + 5 more2026-04-03📄 rehabilitation medicine and physical therapy

Association of Otolithic Integrity With Subjective and Functional Outcomes in Vestibular Rehabilitation: A Pilot Study

This pilot study demonstrates that baseline otolithic structural integrity, assessed via cervical vestibular evoked myogenic potentials, is a critical determinant of subjective recovery in vestibular rehabilitation, suggesting that patients with bilateral structural loss face a physiological "floor" limiting meaningful symptom relief despite functional gains.

Cortes, Y. H., Ramos Maldonado, D., Romo, V. S. + 2 more2026-04-03📄 rehabilitation medicine and physical therapy

Disrupted Bilateral Coordination of Soleus Motor Units during Early Subacute Stroke Rehabilitation

This study demonstrates that early subacute stroke rehabilitation is associated with a significant recovery in bilateral coordination of soleus motor units, where the reduction in inter-limb synchronization lag strongly correlates with improvements in clinical balance scores, despite persistent deficits in postural stability and directional tuning.

Levine, J. T., Yu, X. S., Jones, A. + 6 more2026-04-02📄 rehabilitation medicine and physical therapy

Multidimensional analysis of the clinical spectrum and symptom burden of unexplained myofascial pain

This prospective cross-sectional study demonstrates that symptom burden, particularly physical function and pain catastrophizing, explains the majority of variability in pain intensity and interference among adults with unexplained neck/shoulder myofascial pain, suggesting that multidimensional network analysis can improve clinical risk stratification and shift treatment focus from regional pain contributors to the whole patient.

Sikdar, S., DeStefano, S., Guzman Pavon, M. J. + 10 more2026-04-02📄 rehabilitation medicine and physical therapy

Canadian Association of Cardiovascular Prevention and Rehabilitation (CACPR) Exercise Training Recommendations in Cardiovascular Rehabilitation

This pre-print document outlines the Canadian Association of Cardiovascular Prevention and Rehabilitation's (CACPR) 12 evidence-informed exercise training recommendations for cardiovascular rehabilitation, which reaffirm existing guidelines while introducing new support for High-Intensity Interval Training (HIIT) as a viable and often superior alternative to moderate-to-vigorous continuous training for patients with coronary artery disease, heart failure, and atrial fibrillation.

Hopkins-Rosseel, D., Harris, J., Aver Bretanha Ribeiro, P. + 11 more2026-04-01📄 rehabilitation medicine and physical therapy

Development of an Inventory to Identify Psychosocial Factors Influencing Hand Usage: the CHUC

This study describes the development and validation of the 51-item Changed Hand Usage Concerns (CHUC) inventory, a psychometric tool designed to measure coherent, internally consistent emotional and physical concerns regarding non-preferred hand use to facilitate future rehabilitation efforts for patients with asymmetric impairments.

Soberano, T., Chang, C.-H., Marcori, A. J. + 1 more2026-04-01📄 rehabilitation medicine and physical therapy

Greater sustained sensorimotor function recovery and neuropathic pain reduction with Cognitive Multisensory Rehabilitation compared to adaptive fitness in adults with spinal cord injury: a pilot clinical trial.

This pilot clinical trial demonstrates that an 8-week course of Cognitive Multisensory Rehabilitation (CMR) yields significantly greater and more sustained improvements in sensorimotor function and reductions in neuropathic pain compared to adaptive fitness in adults with spinal cord injury, accompanied by enhanced brain activity and connectivity.

Van de Winckel, A., Carpentier, S. T., Bottale, S. + 9 more2026-04-01📄 rehabilitation medicine and physical therapy

Establishment and Quality Assessment of a Hospital-Associated Disability Database in Japan

This prospective multicenter study in Japan successfully established and assessed the quality of a hospital-associated disability registry database, demonstrating its feasibility for collecting detailed clinical data to support future research on risk factors and prevention strategies for functional decline in older adults.

Hori, S., Wakabayashi, H., Nishioka, S. + 5 more2026-03-31📄 rehabilitation medicine and physical therapy

Improving walking after lumbar spinal stenosis surgery: co-design and single-arm feasibility trial of the STructured Rehabilitation and InDividualised Exercise and Education (STRIDE) programme

This study demonstrates that the co-designed, theory-informed STRIDE rehabilitation programme is acceptable and feasible for improving walking outcomes in patients undergoing lumbar spinal stenosis surgery, showing promising signals of clinical benefit that support progression to a definitive trial.

McIlroy, S., Bearne, L., McCarter, A. + 5 more2026-03-31📄 rehabilitation medicine and physical therapy

CardioAI: An Explainable Machine Learning System for Cardiovascular Risk Prediction and Patient Retention in Nigerian Healthcare Settings

CardioAI is an open-source, explainable machine learning system developed for Nigerian healthcare settings that integrates high-accuracy cardiovascular risk prediction using XGBoost and SHAP analysis with a patient retention module to address critical challenges in disease management and clinic operations.

Gboh-Igbara, D. C.2026-03-31📄 rehabilitation medicine and physical therapy

Cortical activity during preparation and execution of balance recovery behavior in people after mild traumatic brain injury: A preliminary investigation

This preliminary study reveals that individuals with mild traumatic brain injury exhibit distinct cortical signatures during reactive balance recovery, characterized by reduced preparatory beta-burst power and earlier N1 response latencies, suggesting altered neural mechanisms that could inform future rehabilitation strategies.

Palmer, J. A., Lohse, K., Fino, P.2026-03-31📄 rehabilitation medicine and physical therapy

The impact of hospital discharge on physical activity and sedentary behaviour following orthopaedic trauma: An interrupted time series analysis

This interrupted time series study of 31 orthopaedic trauma patients reveals that hospital discharge significantly increases daily physical activity by 27%, demonstrating a positive impact of the home environment on recovery compared to the acute hospital setting.

Kirk, A., Kimmel, L., Lane, T. J. + 2 more2026-03-28📄 rehabilitation medicine and physical therapy

Recovery of Dexterous Motor Control via Non-Monosynaptic Corticospinal Pathways

This study demonstrates that people with post-stroke hemiparesis can regain dexterous motor control through epidural cervical spinal cord stimulation, which utilizes residual non-monosynaptic corticospinal pathways to modulate spinal reflexes and refine muscle activation patterns rather than relying on direct monosynaptic connections.

Sorensen, E., Borda, L., Ostrowski, J. + 10 more2026-03-26📄 rehabilitation medicine and physical therapy

Healthcare professionals collaboration and satisfaction within an innovative primary care network for patients with chronic musculoskeletal pain: a mixed method study

This mixed-methods study evaluates the Network Pain Rehabilitation Limburg (NPRL), finding that while the integrated biopsychosocial primary care model significantly improved communication and team functioning among healthcare professionals treating chronic musculoskeletal pain, sustaining work satisfaction and collaboration requires addressing systemic challenges such as GP workload, reimbursement issues, and the need for broader societal acceptance of the biopsychosocial approach.

Lamper, C., Kroese, M., Mooij, M. d. + 2 more2026-03-25📄 rehabilitation medicine and physical therapy

Physiotherapy service during the COVID-19 pandemic in Nepal: An onsite survey and the lived experience among clinicians

This study reveals that the COVID-19 pandemic significantly disrupted physiotherapy services in Nepal by reducing patient access and worsening conditions, while simultaneously prompting clinicians to adapt through expanded multidisciplinary roles, increased recognition of respiratory care, and the tentative exploration of tele-rehabilitation.

Shakya, N. R., Dahal, S., Shrestha, N. + 2 more2026-03-22📄 rehabilitation medicine and physical therapy