Shape-Independent Fluidization in Epithelial Cell Monolayers
Questo studio sfida il paradigma geometrico vigente dimostrando che la fluidificazione dei monolayer cellulari epiteliali può avvenire in modo indipendente dalla forma cellulare, rivelando che l'adesione cellulare agisce non solo come energia termodinamica ma anche come attrito viscoso cinetico, un meccanismo essenziale per comprendere la transizione solido-fluido.
Pradip K. Bera (Department of Mechanical Engineering, University of Wisconsin - Madison, Madison, WI, USA), Anh Q. Nguyen (Department of Physics, Northeastern University, Boston, MA, USA, Center for Theoretical Biological Physics, Northeastern University, Boston, MA, USA), Molly McCord (Department of Mechanical Engineering, University of Wisconsin - Madison, Madison, WI, USA, Biophysics Program, University of Wisconsin - Madison, Madison, WI, USA), Dapeng Bi (Department of Physics, Northeastern University, Boston, MA, USA, Center for Theoretical Biological Physics, Northeastern University, Boston, MA, USA), Jacob Notbohm (Department of Mechanical Engineering, University of Wisconsin - Madison, Madison, WI, USA, Biophysics Program, University of Wisconsin - Madison, Madison, WI, USA)Mon, 09 Ma🔬 physics