📄 化学

Elucidating the interactions of an unmodified natural clay with cationic and anionic dyes: Toward sustainable remediation

This study elucidates the mechanisms governing the efficient and largely irreversible adsorption of cationic methylene blue and anionic Congo red dyes onto unmodified Cuban natural palygorskite clay, identifying electrostatic, hydrophobic, hydrogen bonding, and supramolecular interactions as the primary drivers for water remediation.

Aramis Rivera, Sheila Alfonso Martín, Dayaris Hernández2026-09-04
📄 化学

Preparation and Pore Structure Characterization of Balsa Wood (Ochroma pyramidale)/GO Composites

本研究表明,利用 Na₂SO₃/NaOH 对巴尔沙木进行预处理,随后通过真空浸渍工艺引入 3‰ 的最佳氧化石墨烯 (GO) 浓度,可制备出具有增强的热稳定性和分级且高度连通的多尺度孔隙结构的复合材料,而偏离这一特定 GO 浓度则会破坏理想的孔隙架构。

Xinyu Li, Shijie Lu, Hongyan Zhu, Shijie Li, Jianguo Zhao2026-09-03
📄 化学

Non-Proteinogenic Amino Acid Catalyzed Green Synthesis of Triazolo[5,1-b]quinazolinone Scaffolds with Promising Anti-inflammatory Activity

本研究报告了以哌啶甲酸为有机催化剂在乙醇中高效、绿色地合成了一系列三唑并[5,1-b]喹唑啉酮衍生物,并确定了特定的氟苯基和萘基类似物作为强效抗炎剂,其在抑制蛋白质变性方面表现优于标准药物双氯芬酸钠。

Dhamodharan Swathi, Vimal Dinesh Vishwa, Peeli Kumar Anjali, Muniyan Ramasamy Kuppusamy, Devendiran Parthiban2026-09-03
📄 化学

NISTmAb-Based Small-Scale RP-HPLC Screening for DAR Adjustment in Cysteine Antibody-Drug Conjugation

本研究展示了一种利用 NISTmAb 标准物质进行的小规模筛选工作流程,用于优化基于半胱氨酸的抗体-药物偶联条件,具体确定了通过减少反相高效液相色谱(RP-HPLC)分析,可以经由调整 TCEP 和连接子-载荷当量来有效地调节药物-抗体比(DAR)。

Yutaka MATSUDA, Monica Leung, Zhala Tawfiq, Veronica Robles, Yuichi Nakahara, Brian A. Mendelsohn2026-09-03