📄 medicine

Structural and physeal integrity, not surgical timing, determines functional outcome after delayed open reduction and Kirschner-wire fixation of neglected paediatric lateral humeral condyle fractures: an ambispective clinical, radiological and MRI study

这项双向回顾性研究表明,对于被忽视的儿童侧肱骨髁骨折,行延迟性切开复位及K针固定术后的功能结局是由肘关节的结构和骨骺完整性决定的,而非由损伤被忽视的时长决定。

Rahul Rai, Shubham Srivastava, Shivam Sinha, Amit Rastogi, Pramod Kumar Singh, Soumya Ranjan Nayak, Sushil Gandhi, Kajal (…)2026-07-10
📄 medicine

Human papillomavirus-associated immune profile of the tumor microenvironment in laryngeal squamous cell carcinoma: a Tunisian cohort study

这项突尼斯的队列研究表明,高危型 HPV 阳性的喉鳞状细胞癌病例表现出一种独特的肿瘤微环境,其特征是与 HPV 阴性病例相比,CD8⁺ T 细胞、FOXP3⁺ 调节性 T 细胞和肿瘤相关巨噬细胞的浸润显著增加。

Nehla Mokni Baizig, Salma Kamoun, Yosr Zenzri, Alia Methnani, Rim Abidi, Yoldz Houcine, Maha Driss2026-07-10
📄 medicine

Association of Lipoprotein(a) With SYNTAX Score in Young Adults Presenting with Acute Coronary Syndrome: A Cross-Sectional Study

这项针对 AIIMS Rishikesh 55 名急性冠状动脉综合征年轻患者的横断面研究表明,升高的脂蛋白(a)水平与以 SYNTAX 评分为衡量标准的冠状动脉造影严重程度增加之间存在显著的正相关性,这表明 Lp(a) 是早发性冠心病风险分层中的一个有价值的标志物。

AKASH SWAIN, BARUN KUMAR, KANIKA KUKREJA, ADITYA AGARWAL, KISHAN MAVANI2026-07-10
📄 medicine

Agreement and device-specific calibration of a single-frequency and a multi-frequency segmental bioelectrical impedance analyzer against dual-energy X-ray absorptiometry for appendicular skeletal muscle mass: a two-center method-comparison study with external validation

这项两中心研究表明,虽然单频和多频生物电阻抗分析仪与双能X射线吸收法相比表现出系统性的、特定设备的偏差,但应用特定设备的校准方程能显著提高其在外部验证中的准确性和低肌肉量分类的准确性,这强调了在未经调整的情况下,BIA和DXA不能互换使用。

Yifei Ouyang, Chang Su, Ziyi Liu, Huijun Wang2026-07-10
📄 medicine

Altered resting-state functional connectivity and network topology in early-stage Parkinson’s disease: associations with depressive symptoms

本研究利用静息态功能磁共振成像(fMRI)和图论分析对PPMI数据进行研究,旨在证明早期帕金森病以特定的功能连接和网络拓扑结构改变为特征,特别是在默认模式网络内部,且这些改变与抑郁症状的严重程度显著相关。

Zahra Khandan Khadem-Reza, Mohammad Amin Shahram, Seyed Amin Ghaemmaghami, Alireza Montazerabadi, Mahtab Khajeh, Seyedeh (…)2026-07-10
📄 medicine

Rethinking anthropometric risk: non-linear associations between body indices and carotid plaque

这项针对立陶宛成年人的研究表明,人体测量学指数(ABSI、BRI 和 BMI)与颈动脉斑块患病率之间的关联是复杂且非线性的,尤其是在男性中,较低的指数值并不总是意味着较低的心血管风险,且往往与较高的代谢异常同时出现。

Ignas Badaras, Roma Puronaite, Egidija Rinkuniene, Vytautas Kasiulevicius, Jolita Badariene, Vilma Dzenkeviciute2026-07-10