📄 medicine

Impact of cardiovascular-kidney-metabolic (CKM) syndrome multistaging on all-cause and cardiovascular mortality in type 2 diabetes: a retrospective cohort study

这项针对 21,918 名中国 2 型糖尿病患者的回顾性队列研究表明,心血管-肾脏-代谢(CKM)综合征的进展阶段与全因死亡率及心血管死亡率的进行性分级升高均呈独立相关,强调了实施阶段化管理策略的必要性。

Qichao Sheng, Huiqin Mei, Guomiao Zhang, Mengtin Yin, Yan Fang, Kailong Liu, Yixin Shou, Xiaoyu Zhang, Chao Zhen, Fang S (…)2026-07-01
📄 medicine

Interpretable Machine Learning for Identifying High SBS-Related Symptom Burden Among Endoscopy-Center Staff: A Multicenter Cross-Sectional Study Across 184 Hospitals

这项多中心研究开发并验证了一个可解释的逻辑回归模型,该模型能够准确识别具有高患病建筑综合征症状负担的内镜中心工作人员,并揭示了工作场所空气质量、心理社会压力以及同事症状是主要的促成因素。

Xianhuang Li, Weixiang Liu, Ruoyun Hu, Yiyi Liu, Tong Wang, Haojun Chen, Ziyi Li, Haixia Liu, Xi Huang, Jiuhong Ma2026-07-01
📄 medicine

Network structure of daily life difficulties in children with attention- deficit/hyperactivity disorder: a cross-sectional network analysis

这项针对1,188名患有ADHD儿童的横断面网络分析显示,日常生活功能障碍与特定的早晨及夜间常规呈现出明显的时序聚类特征,并以这些常规作为核心节点,同时表明育儿压力和家庭适应与这些困难具有相位依赖性关联,从而提示有必要开展基于时间定制且面向家庭系统的干预措施。

Ran Wei, Shanshan Ding, Hua Jin, Yiyuan Chen, Hui Zhong, Lei Xu, Tianyu Lei, Kan Ye2026-07-01
📄 medicine

Model construction and validation of Dual-Energy CT multi-parameters combined with clinical indicators for predicting lymph node metastasis in pancreatic ductal adenocarcinoma

本研究开发并验证了一种结合双能CT多参数(具体为静脉期能量衰减斜率和瘤内坏死)与CA19-9水平的术前预测模型,用于有效预测胰腺导管腺癌的淋巴结转移,展示了良好的诊断准确性和临床应用价值。

HONGJI Zhu, Shuai Ming, Peng Cheng, Wuyang Zhang, Jingyu Li, Bin Wang, Meimei Jiang, Chenglin Zhu, Aiyun Sun, Wei Wei2026-07-01
📄 medicine

Association of the C-reactive Protein–Albumin–Lymphocyte Index With Long-term All-cause Mortality After Percutaneous Coronary Intervention for Acute Coronary Syndrome: A Retrospective Cohort Study

这项针对388例接受经皮冠状动脉介入治疗的急性冠脉综合征患者的回顾性队列研究表明,较高的基线C反应蛋白-白蛋白-淋巴细胞指数与显著较低的长期全因死亡率独立相关,提示其作为风险分层预后生物标志物的潜在应用价值。

Yuan-Bo Zhang, Chi Chen, Tao Zheng2026-07-01
📄 medicine

Unraveling Complex Brain-Behavior Relationships in Alzheimer’s Disease: A Synchronized Multi-metric Analysis of Cognitive Correlates

本研究利用阿尔茨海默病患者的同步多模态成像与神经心理学分析,揭示了一种反直觉的“局部代偿与全局失连”特征,即特定区域内神经活动与连接性的减少反而与较好的认知表现相关联,这表明存在神经效率低下及异常的代偿机制。

Jiayi Liang, Yan Gao, Yang Li, Mengwei Yuan, Fangyuan Yan, Shuo Qu, Li Liu, Xiaowei Ma2026-07-01
📄 medicine

Small-area inequalities in weight excess and obesity among adults in Belo Horizonte, Brazil: a repeated cross-sectional ecological study using Vigitel and synthetic populations

这项生态学研究利用经合成人口数据增强的 Vigitel 调查数据,揭示了巴西贝洛奥里藏特市的超重和肥胖在 2006 年至 2018 年间呈上升趋势,且呈现出由性别与领土脆弱性交织驱动的独特模式,从而证明了小区域监测对于针对性公共卫生规划的价值。

Larissa F Araújo, Jussara M Almeida, Crizian S Gomes, Regina T I Bernal, Marcos A Gonçalves, Gregorio V Rodrigues, Thani (…)2026-07-01
📄 medicine

Anesthesia Modality Affects Clinical Outcomes in Patients with Anterior Circulation Acute Ischemic Stroke Undergoing Endovascular Mechanical Thrombectomy: A Retrospective Study with Propensity Score Matching

这项回顾性倾向评分匹配研究表明,与全身麻醉相比,非全身麻醉可使接受机械取栓术的前循环急性缺血性卒中患者的手术时间缩短、神经功能恢复改善并降低死亡率。

Lijuan Zhou, Xiaoying Pan, Jialin Li, Yuanqiang Q Dai2026-07-01