📄 medicine

Electro-acupuncture combined with adjuvant chemotherapy in gastric cancer (EAGER-2): a protocol for a multicenter randomized controlled trial

EAGER-2研究是一项多中心、受试者盲法、安慰剂对照的随机试验,旨在验证电针结合辅助化疗在改善胃切除术后胃癌患者无病生存期及其他临床结局方面的有效性。

Yuxing Hu, Xuesong Chang, Xiaoshu Chai, Ziyan He, Jiaming Liu, Zexing Zhang, Tianlin Wang, Yadong Chen, Yihan He, Yanjua (…)2026-07-12
📄 medicine

Dietary and chemical factors concurrently related to overweight in children and young adults – A cross-sectional Exposome-Wide Association Study (ExWAS)

这项针对超过41,000名2至25岁美国受试者的横断面ExWAS研究识别出了91种与超重相关的饮食及化学暴露因素,并强调虽然大多数一致因素都与较低的几率相关(例如纤维、铜和叶酸),但很少有因素能一致地与较高的几率相关(显著包括γ-生育酚和可替丁)。

Anne Kristine Christensen, Cecilia Ramlau-Hansen, Thorkild Sorensen, Olivier Jolliet, Christina Dahm2026-07-12
📄 medicine

Unveiling the Biomechanics of a Novel Distalizer Appliance: Finite Element Analysis of Stress Distribution and Molar Displacement Running title: Biomechanical Evaluation of a Novel Distalizer

本研究利用有限元分析证明,一种向第一和第二上颌磨牙同时施加相等力量的新型腭侧支托种植体支持远中移动装置,与仅向第一磨牙施加力量的装置相比,具有更均匀的应力分布、更大的整体位移以及更优越的垂直控制。

Mostafa K. Sofar, Mushriq Abid2026-07-12
📄 medicine

Prognostic differences of refractory/relapsed diffuse large B-cell lymphoma with bulky and non-bulky disease in the chimeric antigen receptor T cell therapy era

在 CAR-T 疗法时代,伴有体积大(bulky)的复发/难治性弥漫大 B 细胞淋巴瘤患者的总体生存期较非体积大患者更差,尽管自体造血干细胞移植与 CAR-T 的结合显著改善了两组患者的预后。

Xiying Huang, Dongliang Zhang, Guihua Lu, Xiong Ni, Gusheng Tang, Libing Wang, Wenqin Yue, Li Chen, Jie Chen, Tao Wang (…)2026-07-12
📄 medicine

Cause of disease mediates the relationship between socioeconomic status and laryngotracheal stenosis outcomes: A retrospective cohort study in South Africa

这项在南非进行的回顾性队列研究表明,虽然社会经济地位并不直接预测喉气管狭窄的预后,但它显著影响了该疾病的病因学,而病因学进而通过一种被称为“社会决定因素的病因嵌入”的机制,中介了临床严重程度和治疗效果。

Gerhard Johan Klopper, Lufunda Lukama, Oladele Vincent Adeniyi2026-07-12
📄 medicine

The «SPA-CE» Classification for Glenoid Bone Loss in Reverse Shoulder Arthroplasty: A CT-Based Analysis of 211 Shoulders

本研究引入并验证了基于 CT 的 SPA-CE 肩胛盂骨丢失分类系统,证明了其作为一种以治疗为导向的框架,能够将特定的缺损模式与适当的重建策略相关联,并提供了比 Walch 等现有系统更丰富的形态学细节。

Dmitry A. Samkovich, Georgii A. Airapetov, Vadim F. Naidanov, Ivan A. Dmitrov, Alexey P. Prizov, Asadula R. Abasov, Arme (…)2026-07-12