📄 Category

anesthesia

7 papers

Anesthesia is the vital science that keeps patients safe and comfortable during medical procedures, managing everything from pain relief to unconsciousness. This field explores how different drugs interact with the nervous system and how clinicians tailor these interventions to individual needs. On Gist.Science, we bring the latest discoveries from this critical area directly to you, stripping away complex barriers to understanding.

Every new preprint in this category arrives from medRxiv, where researchers share their findings before formal publication. Our team processes each of these documents to provide both accessible plain-language explanations and detailed technical summaries, ensuring that groundbreaking insights are available to everyone, not just specialists. Below are the latest papers in anesthesia, offering fresh perspectives on patient care and drug development.

📄 anesthesia

Maintenance Anesthetics and Postoperative Delirium in Older Adults Undergoing General Anesthesia: A Systematic Review and Network Meta-analysis of Randomized Trials

This protocol outlines a systematic review and network meta-analysis of randomized trials designed to compare the effectiveness of various maintenance anesthetics (including remimazolam, propofol, and volatile agents) in preventing postoperative delirium among older adults, with the goal of establishing an evidence-based ranking to guide clinical practice.

Miyake, T., Kanemaru, E., Sasaki, K., Noma, H., Mihara, T.2026-07-26
📄 anesthesia

Serum potassium elevation and acute respiratory acidosis during thoracoscopic esophagectomy with intrathoracic carbon dioxide insufflation: a multicenter retrospective observational study

This multicenter retrospective study reveals that thoracoscopic esophagectomy with intrathoracic carbon dioxide insufflation induces a clinically significant increase in serum potassium alongside acute respiratory acidosis, a phenomenon that persists even after accounting for metabolic stress and suggests the need for routine potassium monitoring during procedures involving permissive hypercapnia.

Okamoto, S., Tochii, T., Hotta, R., Nakamura, K., Nakada, J., Note, H.2026-07-08
📄 anesthesia

Dexmedetomidine as a Perioperative Adjunct in Valvular Cardiac Surgery

This retrospective study of 154 patients undergoing valvular cardiac surgery found that perioperative dexmedetomidine infusion significantly improved intraoperative hemodynamic stability by attenuating heart rate responses to surgical stress, though it did not demonstrate statistically significant reductions in postoperative complications, ICU length of stay, or mortality compared to the control group.

Harshappan, J., Umbarkar, S., Pimpalkhute, P., Pimpalkhute, P., Upadhyay, R., Kacha, J. S.2026-07-03
📄 anesthesia

The Effect of Sex on median effective concentration of ropivacaine for ultrasound-assisted caudal block in the elderly undergoing Anorectal Surgery

This double-blind prospective study of 40 elderly patients undergoing anorectal surgery demonstrates that the median effective concentration (EC50) of ropivacaine for ultrasound-assisted caudal block is significantly higher in females (0.281%) than in males (0.263%), indicating a notable gender difference in anesthetic requirements for this population.

Wang, F., Qu, M., Zhao, W., He, Y., zhou, h., Zhang, L.2026-06-26
📄 anesthesia

Study protocol Effects of Philips Visual Patient Avatar on vital sign deviations and audible alarm burden in perioperative care: a dual-centre, quasi-experimental pre-post big-data study protocol (NewYork-Presbyterian/Weill Cornell and University Hospital Zurich)

This study protocol outlines a dual-centre, quasi-experimental pre-post big-data investigation designed to systematically quantify the impact of the Philips Visual Patient Avatar on vital sign deviations and audible alarm burden in perioperative care, aiming to determine if this avatar-based visualization improves situation awareness and reduces cognitive load compared to conventional monitoring.

Jiang, S. Y., Roche, T. R., Cybulski, K., Dugac, G., Meier, L., Tangel, V. E., Ebensperger, M., Maskos, A., Tucci, M., N (…)2026-05-21
📄 anesthesia

COMPARISON OF POSTOPERATIVE PAIN SEVERITY AND ANALGESIC CONSUMPTION WITHIN 24 HOURS BETWEEN PRIMARY AND REPEAT CESAREAN SECTIONS UNDER SPINAL ANESTHESIA: A PROSPECTIVE COHORT STUDY

This prospective cohort study conducted in Ethiopia found that women undergoing repeat cesarean sections under spinal anesthesia experience significantly higher postoperative pain severity and require greater analgesic consumption within the first 24 hours compared to those having primary cesarean sections.

Bitewlign, M. Z., Gemeda, L. A., Delile, S. T., Seife, M. A., Zeleke, M. E., Gebrewahd, T. H., Gebreslase, L. G., Tesfag (…)2026-03-06