Latest papers — 2026-04-26

Baseline characteristics of the population-based cohort in Iga City - the Iga City Cohort Study

The Iga City Cohort Study is a population-based genomic study involving 1,516 participants recruited between 2013 and 2014 to collect lifestyle, socioeconomic, and biological data to establish evidence for personalized disease prevention.

Hishida, A., Shirai, Y., Kageyama, I., Kawai, S., Sasakabe, T., Lin, Y., Yamamoto, M., Nishio, M., Okuda, H., Tanaka, K., Tamura, T., Nagayoshi, M., Matsunaga, T., Hamajima, N., Wakai, K.2026-04-26📊 epidemiology

📄 geriatric medicine — 1 papers

Human aging reflects increases in entropy across organ networks

By utilizing a new metric called Distance of Covariance (DISCO), this study demonstrates that human aging is characterized by a systemic increase in entropy that spreads across interconnected organ networks, suggesting that aging is a failure of integrated homeostatic coordination rather than a collection of independent organ-specific processes.

Hao, M., Zhang, H., Li, Y., Huang, Y., Wu, J., Zhang, S., Guo, X. A., Li, X., Hu, Z., Li, X., Jiang, S., Tanner, K. T., Rutenberg, A., Chen, J., Bao, Z., Wang, J., Huang, Y., Cohen, A. A., Jin, L., Wa (…)2026-04-26📄 geriatric medicine

🔬 oncology — 1 papers

Time-related biases in observational studies : an illustration with COVID-19 vaccination during immune checkpoint inhibitor therapy

This paper demonstrates how improper specification of study timelines in observational research can lead to erroneous conclusions, using a re-analysis of a COVID-19 vaccination study in cancer patients to show that applying a proper target trial emulation framework significantly attenuates the previously reported survival benefits.

Dumas, E., Gougis, P., Gasparollo, L., Spano, J.-P., Stensrud, M. J.2026-04-26🔬 oncology