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Hybrid Statistical Modeling and Machine Learning Ensemblers for Interpretable HIV Viral Load Prediction Among Clients on Antiretroviral Therapy

This study develops and validates a Stacking-based ensemble machine learning model using 5.7 million viral load records from Uganda to accurately predict the next visit viral load for ART clients, achieving superior performance with an R² of 0.85 and utilizing LIME for model interpretability.

Muhire Jacob, Jjingo Daudi, Galiwango Ronald, Joyce Nakatumba-Nabende, Aloysious Ssemaganda, Isaac Ssewanyana2026-09-10
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Separating local scale dependence from regional mixing in urban block-size distributions

This paper introduces a model-independent workflow to distinguish genuine local scale dependence from artificial trends caused by regional mixing in urban block-size distributions, demonstrating through a comprehensive analysis of Tokyo that while regional heterogeneity flattens the distribution tail, smaller blocks exhibit significant local steepening that cannot be explained by compositional effects alone.

Hiroyuki Shima, Yuri Akiba2026-09-10
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Practitioner Allegiance Risk Scale (PARS-6): Development of a Theory-Informed Instrument for Screening Investigator Allegiance-Related Risk Across Intervention Research

This paper presents the theoretical development and structure of the Practitioner Allegiance Risk Scale (PARS-6), a new six-item instrument designed to systematically screen and document investigator allegiance-related characteristics during data extraction in systematic reviews of intervention research, while explicitly clarifying that it serves as a descriptive risk indicator rather than a definitive measure of bias.

Balaganesh Gopurala, Om Vrishank Gopurala, Suryaprathap Gopurala, Cathal Walsh2026-09-09
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Comparative and Forecast Analysis of Research Productivity among Philippine State Universities: A SciVal-Based Bibliometric Assessment (2015–2025)

This study utilizes SciVal bibliometric data and forecasting models to reveal that while Philippine State Universities have significantly increased publication volumes from 2015 to 2025, substantial and persistent regional disparities in research output and impact—led by Region III—will continue through 2030 without targeted capacity-building investments rather than uniform incentives.

Brandon Obenza, Eduard M. Albay, Joel B. Mangaba, Rose Nonette C. Capadosa, Lianne Angelico C. Depante, Leo Mendel D. Ro (…)2026-09-09
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Conditional Sign Randomization with Estimated Whitening in Gaussian Kinship Models

This paper proposes a conditional sign randomization method with estimated whitening for Gaussian kinship models that enables computationally efficient, finite-sample level-controlled gene-set association testing by leveraging sign-symmetry and reusable calibration across a sign orbit, while explicitly distinguishing its global null inference target from competitive enrichment or causal gene discovery.

Siyu Guo, Ruixiang Zhang, Benfan Lin, Yunfan Zhang, yu wang2026-09-09
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Improved MGLR control charts based on Klein’s sensitizing rules for joint mean and dispersion monitoring under measurement error

This paper proposes and evaluates two enhanced multivariate generalized likelihood ratio (MGLR) control charts that integrate Klein's 2-of-2 and 2-of-3 sensitizing rules to effectively monitor simultaneous shifts in process mean and dispersion while explicitly accounting for the detrimental impact of measurement error.

Mohammad Reza Maleki, Mohammad Nikoogoftar, Hossein Eghbali, Majid Jafari2026-09-08
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A structural equation formulation for general quasi-periodic Gaussian processes

This paper introduces a structural equation formulation for general quasi-periodic Gaussian processes that simplifies generation and forecasting while reducing computational complexity from O(k2p2)\mathcal{O}(k^2 p^2) to O(p2)\mathcal{O}(p^2), offering a scalable and consistent approach for analyzing diverse natural and physiological signals.

Unnati Nigam, Radhendushka Srivastava, Faezeh Marzbanrad, Michael Burke2026-09-08