50 papers
This study demonstrates that evanescent wave-based optical manipulation can non-invasively detect significant glucose-induced reductions in red blood cell mobility, suggesting its potential as a tool for probing membrane mechanical properties.
This study demonstrates a robust, label-free methodology using lens-free digital in-line holographic microscopy to achieve high-resolution 3D volumetric reconstruction and precise morphological characterization of native Chilean pollen grains, offering a scalable solution for automated melissopalynology and biodiversity assessment.
This paper presents a nondestructive method for assessing kiwifruit ripeness using near-infrared pulse illumination at 800 nm, introducing two nonmonotonic indices (relative ripeness and the first Wasserstein distance) to quantify temporal light profile changes observed over a ten-day period.
This paper proposes that quantum tunneling, rather than classical diffusion, is the fundamental mechanism enabling high-flux ion transport in biological channels, thereby resolving the long-standing discrepancy between theoretical predictions and experimental conductance rates.
By applying model selection and dynamical systems theory to body temperature data from a hibernating Arctic ground squirrel, researchers identified a low-dimensional, environmentally sensitive control architecture that not only explains interbout arousals but also qualitatively predicts temperature modulation patterns across diverse species including birds, shrews, and bears.
This paper applies Prigogine's thermodynamics of open systems to formulate a law for individual organism growth and development, demonstrating through experimental comparison that specific entropy decreases across the evolutionary sequence from yeast to birds.
This paper introduces "Pufflets" as inertial counterparts to Stokeslets to demonstrate that metachronal waves of cilia can drive highly efficient particle transport through inertial coasting, a mechanism impossible in low-Reynolds-number Stokes flow.
This paper investigates the over-damped dynamics of chiral active elastic filaments, deriving sixth-order nonlinear equations that reveal dynamic multi-stability in their shapes, and validates these theoretical predictions through linear stability analysis and numerical simulations.
This study utilizes an extended vertex model to demonstrate that cell-cell adhesion acts as a double-edged sword in tissue dynamics, where its energetic component promotes cell migration by lowering rearrangement barriers, while its dissipative component induces jamming and suppresses motion, thereby governing the balance between tissue fluidity and rigidity.
This paper introduces a self-consistent, density-of-states-weighted decoherence probe formalism that resolves limitations in existing charge transport models for DNA by generating physically accurate, energy-dependent scattering rates that avoid unphysical broadening and spurious energy levels.
This paper establishes a Newtonian-like framework for interacting spiral waves in excitable media, defining a time-varying "mass" and collision-based forces that govern their drift and complex N-body dynamics, with significant implications for understanding cardiac fibrillation.
This study employs network theory to analyze a MYH9-focused chemical library, demonstrating that multi-descriptor community detection reveals a robust, consensus-stable core of compounds that can be prioritized for drug repurposing in MYH9-related nephritis.
This study challenges the prevailing geometric paradigm of epithelial fluidization by demonstrating that reducing cell-cell adhesion can trigger a shape-independent transition to a fluid state, necessitating a revised theoretical model that accounts for adhesion's dual role in both interfacial energy and kinetic viscous drag.
The paper introduces Programmable Acoustic Standing-wave Transfection (PAST), a non-invasive microfluidic platform that utilizes dynamically programmable ultrasonic fields to reversibly permeabilize cell membranes and enhance intracellular delivery of biomolecules in cell clusters with high viability and tunable transport rates.
BInD is a knowledge-guided diffusion model that co-generates molecules and their interactions with target proteins to achieve balanced multi-objective optimization in structure-based drug design, outperforming existing methods across key criteria like binding affinity, molecular properties, and local geometry.
This paper introduces a high-precision 3D cellular force measurement technique that utilizes fluorescent nanodiamonds to directly quantify micropillar rotational angles via optically detected magnetic resonance and laser polarization modulation, thereby overcoming the resolution limits and deformation assumptions of conventional displacement-based methods.
This paper presents a quantum-inspired extension of the GenomeBits model that characterizes finite (0,1) binary sequences, such as genome data, by treating them as wavefunctions to reveal sound-wave-like features in their real and imaginary spectra.
This paper presents an overview of GenomeBits, a physics-inspired signal analysis tool that utilizes Discrete Fourier Transform and quantum-based extensions to map nucleotide sequences into numerical signals, successfully revealing intrinsic genomic features, mutation patterns, and unique "order-disorder" transitions in viral genomes such as SARS-CoV-2 variants and Monkeypox.
This paper introduces a novel entropy production estimator for continuous systems with limited resolution that relies solely on the frequency and duration of particle transitions across spatial regions, eliminating the need for Markovian events or discrete underlying dynamics.
This study demonstrates that tabletop extreme ultraviolet (EUV) ptychography provides a powerful, label-free, and quantitative imaging platform with 44 nm resolution to reveal nanoscale morphological and compositional changes in *Escherichia coli* and *Bacillus subtilis* under physiological and antibiotic stress.