Initial Performance of a Long Axial FOV PET with TOF and DOI capabilities: IMAS system

This paper presents the design, construction, and initial performance evaluation of the IMAS system, a long axial field-of-view PET prototype that uniquely combines time-of-flight and depth-of-interaction capabilities, demonstrating sub-4 mm spatial resolution and improved tumor identification in pilot clinical results despite some performance limitations attributed to data transfer bottlenecks.

Antonio J. Gonzalez, Alvaro Anreus-Valero, David Sanchez, Santiago Jiménez-Serrano, Marta Freire, Andrea Gonzalez-Montoro, Edwing Y. Ulin-Briseno, Neus Cucarella, John Barrio, Andrew Laing, Jorge Álamo, Julio Barbera, Luis F. Vidal, Marc Gil, Jose M. Benlloch, Alfonso Rios, Luis Marti Bonmati, Irene Torres-EspallardoWed, 11 Ma🔬 physics

Exploring Strategies for Personalized Radiation Therapy Part IV: An Interaction-Picture Approach to Quantifying the Abscopal Effect

This paper introduces a quantum mechanics-inspired interaction-picture framework to quantify the abscopal effect as a continuous, stochastic phenomenon in the context of PULSAR, enabling individual-level analysis of tumor interactions and standardized cross-study comparisons in preclinical models.

Hao Peng, Laurentiu Pop, Kai Jiang, Faya Zhang, Debabrata Saha, Raquibul Hannan, Robert TimmermanWed, 11 Ma🧬 q-bio

Recent application studies of an INTPIX4NA SOIPIX detector-based X-ray camera using an SiTCP-XG 10GbE-based high-speed readout system at KEK facilities

This paper reports on the development of a high-speed, high-resolution X-ray camera based on the INTPIX4NA SOIPIX detector and a SiTCP-XG 10GbE readout system, demonstrating its successful application in three recent experiments at KEK facilities: X-ray zooming microscopy, phase-contrast imaging, and nondestructive lithium detection in battery materials.

Ryutaro Nishimura, Noriyuki Igarashi, Daisuke Wakabayashi, Yuki Shibazaki, Yoshio Suzuki, Keiichi Hirano, Hiromi Miki, Akio Yoneyama, Hiroshi Sugiyama, Kazuyuki Hyodo, Izumi Umegaki, Koichiro Shimomura, Yasuo AraiWed, 11 Ma🔬 physics.optics

Efficient Vision Mamba for MRI Super-Resolution via Hybrid Selective Scanning

This paper proposes "Efficient Vision Mamba," a computationally lightweight deep learning framework that combines multi-head selective state-space models with hybrid scanning to achieve state-of-the-art MRI super-resolution performance while drastically reducing parameters and computation compared to existing methods.

Mojtaba Safari, Shansong Wang, Vanessa L Wildman, Mingzhe Hu, Zach Eidex, Chih-Wei Chang, Erik H Middlebrooks, Richard L. J Qiu, Pretesh Patel, Ashesh B. Jani, Hui Mao, Zhen Tian, Xiaofeng YangTue, 10 Ma🔬 physics

Synthetic Data in MR Spectroscopy: Current Practices, Applications, and Considerations

This paper, authored by the ISMRM MRS Synthetic Data Working Group, reviews and evaluates current practices, applications, and considerations for generating and utilizing synthetic data in Magnetic Resonance Spectroscopy to address challenges such as limited training data, software validation, and the optimization of acquisition and deep learning models.

John T. LaMaster, Aaron T. Gudmundson, Alireza Abaei, Seyma Alcicek, Arturo Alvarado, Ovidiu Andronesi, Tiffany K. Bell, Wolfgang Bogner, Hanna Bugler, Alexander R Craven, Cristina Cudalbu, Alma Davidson, Christopher W. Davies-Jenkins, Dinesh Deelchand, Richard A. E. Edden, Morteza Esmaeili, Candace C Fleischer, Abdelrahman Gad, Guglielmo Genovese, Saumya Gurbani, Ashley D. Harris, Pierre-Gilles Henry, Kay Chioma Igwe, Ajin Joy, Margarida Julià-Sapé, Hyeonjin Kim, Roland Kreis, Fan Lam, Karl Landheer, Bernard Lanz, Chu-Yu Lee, Clémence Ligneul, Julian P. Merkofer, Jack J. Miller, Jessie Mosso, Stanislav Motyka, Eloïse Mougel, Paul G. Mullins, Saipavitra Murali-Manohar, Chloé Najac, Shinichiro Nakajima, Georg Oeltzschner, Esin Ozturk-Isik, Marco Palombo, Ulrich Pilatus, Justyna Platek, Emma Van Praagh, Xiaobo Qu, Rudy Rizzo, Christopher T. Rodgers, Esau Poblador Rodriguez, Yeison Rodriguez, Manoj K Sammi, Dennis M. J. van de Sande, Manoj Kumar Sarma, Francesca Saviola, Anouk Schrantee, Amirmohammad Shamaei, Dunja Simicic, Brian J Soher, Nico Sollmann, Yulu Song, Jeffrey A Stanley, Bernhard Strasser, Antonia Susnjar, Kelley M. Swanberg, M. Albert Thomas, Ivan Tkáč, Zhangren Tu, Paul J. Weiser, Mark Widmaier, Martin Wilson, Christopher J. Wu, Lijing Xin, Helge J. Zöllner, \.Ipek Özdemir, MRS Synthetic Data Working Group, Antonia KaiserTue, 10 Ma🔬 physics

Extending gPET for Multi-Layer PET Simulation

This paper presents an extension of the GPU-accelerated Monte Carlo toolkit gPET to support flexible multi-layer detector geometries for Depth-of-Interaction (DOI) encoding, demonstrating through validation that the new framework enables efficient simulation and optimization of PET systems with significantly improved radial spatial resolution while maintaining comparable sensitivity and runtime performance.

Satzhan Sitmukhambetov, Junwei Du, Mingwu Jin, Yujie ChiTue, 10 Ma🔬 physics

Ultra-Sharp Upright Photon Radiotherapy via Low Energy Extended Distance: An Alternative to FLASH for high flux Sources

This study demonstrates that delivering low-energy (2.5 MV) photon beams at an extended source-to-patient distance (4 m) in an upright configuration achieves significantly sharper penumbra, lower surface dose, and higher peak-to-valley ratios in spatially fractionated plans compared to standard 6 MV coplanar radiotherapy, offering a viable alternative to FLASH for high-flux sources.

Lloyd E Kamole Ghomsi, Clinton Gibson, Veng-Jean Heng, Ramish M Ashraf, Lawrie SkinnerTue, 10 Ma🔬 physics.app-ph

Moiré Artifact Reduction in Grating Interferometry Using Multiple Harmonics and Total Variation Regularization

This paper presents an image recovery algorithm that utilizes multiple harmonics and total variation regularization to estimate true phase stepping positions, effectively eliminating Moiré artifacts in attenuation, differential-phase, and dark-field images generated by grating interferometers.

Hunter C. Meyer, Joyoni Dey, Conner B. Dooley, Murtuza S. Taqi, Varun R. Gala, Christopher Morrison, Victoria L. Fontenot, Kyungmin Ham, Leslie G. Butler, Alexandra NoelThu, 12 Ma🔬 physics.optics

Controlled kHz laser-driven electron irradiations for pre-clinical applications

This paper reports the first successful in-air irradiation of biological samples using stable, kHz laser-driven electron beams, demonstrating promising pre-clinical results of normal tissue sparing in zebrafish embryos while maintaining anticancer efficacy in glioblastoma cells, thereby marking a significant milestone toward the clinical translation of laser-plasma accelerators.

C. M. Lazzarini, M. Favetta, E. R. Szabo, I. Zymak, L. V. N. Goncalves, M. Jech, S. Lorenz, M. Nevrkla, J. Sisma, A. Spadova, F. Vitha, R. Antipenkov, P. Bakule, A. Grenfell, V. Sobr, W. Szuba, J. Dudas, A. Ebert, R. Molnar, R. Polanek, S. V. Bulanov, K. Hideghety, G. M. GrittaniThu, 12 Ma🔬 physics

Information-Theoretic Spectroscopy: Universal Sparsity of Extinction Manifold and Optimal Sensing across Scattering Regimes

This paper demonstrates that the optical extinction manifold of dielectric materials exhibits intrinsic sparsity best captured by the Discrete Cosine Transform rather than the FFT, enabling a compressed sensing architecture that achieves high-fidelity material reconstruction with a 51–94% reduction in hardware sensors by overcoming traditional Nyquist limits.

Proity Nayeeb AkbarThu, 12 Ma🔬 physics.app-ph

Sparse probabilistic evaluation for treatment planning: a feasibility study in IMPT head & neck patients

This feasibility study demonstrates that Sparse Probabilistic Evaluation (SPE), a computationally efficient method using a predefined error grid, achieves sufficient accuracy for probabilistic treatment planning in IMPT head and neck patients while maintaining clinically acceptable computation times.

Jenneke I. de Jong, Steven J. M. Habraken, Albin Fredriksson, Johan Sundström, Erik Engwall, Sebastiaan Breedveld, Mischa S. HoogemanMon, 09 Ma🔬 physics