A Control-Theoretic Model of Damage Accumulation and Boundedness in Biological Aging
This paper proposes a control-theoretic model of biological aging that decomposes damage into regulatable and information-limited classes, demonstrating that sustained healthspan requires endogenous repair to exceed regulatable damage production while engineered interventions must actively bound information-limited damage, a finding supported by sensitivity analyses showing the latter's dominance in driving asymptotic aging rates.