Simulating nationwide coupled disease and fear spread in an agent-based model

This paper presents an agent-based model within the EpiCast framework that simulates the coupled dynamics of disease and fear transmission, demonstrating how non-local fear spread via media combined with strong behavioral responses can generate multiple epidemic waves and highlighting the critical importance of accounting for these feedback loops in outbreak management.

Joy Kitson, Prescott C. Alexander, Joseph Tuccillo + 5 more2026-03-10🧬 q-bio

Bounds for survival probabilities in supercritical Galton-Watson processes and applications to population genetics

This paper develops a method to derive simple, analytically explicit upper or lower bounds for the survival probability of beneficial mutations in supercritical Galton-Watson processes by approximating their generating functions with fractional linear ones, and applies these results to model the evolution of quantitative traits under directional selection in finite populations.

Reinhard Bürger2026-03-10🧬 q-bio

A hybrid discrete-continuum modelling approach for the interactions of the immune system with oncolytic viral infections

This paper presents a hybrid discrete-continuum modeling framework that couples a stochastic agent-based model with partial differential equations to investigate the spatial dynamics of oncolytic virotherapy and immune system interactions, revealing that while both models generally agree, stochastic effects and the timing of immune responses are critical factors that can significantly influence therapeutic efficacy.

David Morselli, Marcello E. Delitala, Adrianne L. Jenner + 1 more2026-03-10🧬 q-bio

When minor issues matter: symmetries, pluralism, and polarization in similarity-based opinion dynamics

This paper introduces a stochastic agent-based model of opinion dynamics incorporating heterogeneous issue weights and both attractive and repulsive social forces, revealing that even minor issues can destabilize consensus and drive polarization or pluralism depending on similarity thresholds, while offering symmetry-based insights and strategies to mitigate polarization through diversified discourse.

Brian Mintz, Daniel Simonson, Dominik Wodarz + 2 more2026-03-06🔬 physics