📄 medicine

Neuropsychological and Autonomic Correlates of Chronic Stress in Dermatological Patients: A Comparative Analysis of GABAergic Therapy Regimens

这项针对100例慢性压力皮肤科患者的前瞻性研究表明,虽然全身性与全身加局部联合的GABA能疗法均能有效恢复自主神经平衡和神经心理功能,但联合疗法在加速外周微循环与中枢神经动力学正常化方面可能具有潜在优势。

A. S. Smitneva, I. V. Reverchuk¹, Svetlana Horemans2026-07-07
📄 medicine

Longitudinal plasma metabolomics identifies metabolic signatures of early recurrence and platinum resistance in advanced ovarian cancer

本研究利用纵向血浆核磁共振(NMR)代谢组学技术,识别了与晚期卵巢癌早期复发和铂类耐药相关的特定代谢特征,并证明将这些代谢生物标志物与临床数据相结合,相比仅使用临床因素,能显著提高预测准确性。

Victoire Bondeville, May-Britt Tessem, Okan Gultekin, Guro F. Giskeødegård, Nina Groes Kofoed, Johan A. Westerhuis, Kais (…)2026-07-07
📄 medicine

Seizure Prophylaxis Versus Epilepsy Prevention After Acquired Brain Injury: A Cross-Sectional ClinicalTrials.gov Registry Analysis, 2000-2026

这项针对 2000 年至 2026 年间 ClinicalTrials.gov 记录的横断面分析表明,获得性脑损伤后癫痫发作的研究格局呈现出碎片化特征,且在急性癫痫预防与长期癫痫预防之间存在显著混淆,因此未来的试验需明确区分这些终点并提高报告标准。

Anil Chimakurthy, Viswabhaskar Susarla, Jeet Hemantkumar Chaudhary, Om Desai2026-07-07
📄 medicine

Assessment of the implementation level of Infection Prevention and Control (IPC) for the prevention of antimicrobial resistance in referral hospitals: the case of Kamenge University Teaching Hospital (CHUK), Gitega Regional Hospital, and Natwe Turashoboye Hospital in Karusi, Burundi

这项针对布隆迪三家转诊医院的横断面研究表明,感染预防与控制(IPC)的实施水平严重不足,其全球评分在100分中仅为31至42分,且在治理、监测和人员资质方面存在显著缺陷。

Prosper Niyonkuru, Niyonsaba Vestine, Fidel BIGIRIMANA2026-07-07
📄 medicine

AI in the clinic: a scoping review of AI and clinical expertise

这项针对 2022 年以来 58 项实证研究的范围综述表明,尽管人工智能工具显著提升了医生的临床表现——尤其是对于新手而言——但目前的证据并不支持对人工智能导致技能退化的担忧,尽管仍需进一步的纵向研究以全面评估其对临床专业能力的长期影响。

Eric Owens, Oliver Buchholz, Yasmine Douar, Vibhuti Thapliyal, Alessandro Blasimme2026-07-07
📄 medicine

Lower Serum Free Triiodothyronine is Independently Associated with Isolated Left Anterior Descending Coronary Slow Flow:A Cross-Sectional Study

这项横断面研究表明,较低的血清游离三碘甲状腺素(FT3)水平与孤立性左前降支冠状动脉血流缓慢具有独立的关联性并展现出中度的预测价值,提示甲状腺激素缺乏与冠状动脉微血管功能障碍之间可能存在联系。

Jinpeng Zhong, Liwu Dai, Xiaohong Lu, Jianzhong Ruan, Yazhou Li, Yan Lu, Yunqing Chen2026-07-07
📄 medicine

Can a constrained AI clinical decision-support pipeline generate meal plans rated as highly as dietitian-designed plans? A blinded professional evaluation

一项针对 54 名注册营养师进行的盲测专业评估发现,由受限 AI 流水线生成的饮食计划被评定为与人类营养师设计的方案水平相当,且在某些领域甚至更高,评估人员无法可靠地分辨两者之间的来源。

Ellis Wollis Malta Abhulime, Diogo Thimoteo da Cunha, Vicente Rossi Monaco, Rafael Delgado de Melo, Fabiana Braga Benatt (…)2026-07-07
📄 medicine

Incidence and Detection of ESC-Defined Cardiotoxicity Among Early-Stage Breast Cancer Patients Receiving Anthracycline-Based and Anti-HER2 Therapy in Qatar

这项针对卡塔尔133例早期乳腺癌患者的研究显示,在接受蒽环类药物和抗HER2治疗后,符合欧洲心脏病学会(ESC)定义的心脏毒性发生率极高(69.2%),且大多数病例为无症状,主要通过全球纵向应变和生物标志物升高而非传统的射血分数下降来检测,这强调了在该人群中进行多模态监测的紧迫需求。

Asma Mohammad Younus Al Bulsuhi, Wafaa Shehada, Salma Suliman, Jassim Zaheen Shah, Rasha Kaddoura, Kalpana Singh, Nima A (…)2026-07-07