TAOK3 marks an invasion‑competent epithelial subset in cervical cancer, and its inhibition restrains tumor growth, sensitizes to paclitaxel, and remodels the immune microenvironment
本研究确定了 TAOK3 是宫颈癌中驱动肿瘤进展和免疫逃逸的侵袭性上皮细胞亚群的关键标志物,并证明抑制该蛋白可抑制肿瘤生长、提高肿瘤对紫杉醇的敏感性,并将微环境重塑为抗肿瘤免疫状态。