🧬 biology

Covalent versus noncovalent chlorogenic acid binding: Divergent effects on the gastrointestinal fate and allergenic potential of soybean 7S globulin

这项研究揭示了绿原酸通过不同的机制调节大豆7S球蛋白的消化率和致敏性,其中非共价结合增强了抗原性片段的蛋白水解清除,而共价结合则掩盖了IgE表位,为设计低过敏性大豆原料提供了一个战略框架。

Penghui Zhang, Ze Yun, Jiahao Li, Xin Yuan, Jingwen Ma, Lingjun Ma, Fang Chen, Xiaosong Hu, Junfu Ji2026-09-11
🧬 biology

Unsaturated Fatty Acid-Rich Diets Modulate Plasticity in Pre-Adult Fitness, Behavior, and Development in Drosophila melanogaster

这项研究表明,富含不饱和脂肪酸的饮食会加速黑腹果蝇的预成虫发育并增加幼虫活性,同时降低蛹化高度和存活率,这表明存在一种使通常相关的生命史特征发生脱钩的发育可塑性。

Aradhana Joshi, Pooja Ramakrishnan, Sunil Kumar Birua, Shanmugapriya Chandrasekaran, Anusri Nakkeiran, Pankaj Yadav2026-09-11
🧬 biology

In vitro antibacterial activity of ethanolic peel and seed extracts of sweet orange (Citrus sinensis) against Staphylococcus aureus and Escherichia coli

本研究表明,甜橙皮和种子的乙醇提取物对金黄色葡萄球菌和埃希氏大肠杆菌表现出浓度依赖性的抗菌活性,其中果皮提取物的效果最为显著,从而验证了这些农业废弃物作为低成本抗菌化合物来源的潜力。

Gabriel Robert Golola, Richard Rayson Sanga, Paul Samson Buyugu, Veronica Emanuel Masawe, David Joshua Junior, Mussa All (…)2026-09-11
🧬 biology

Integrated genomic and functional characterization of salt stress adaptation and plant growth-promoting traits in the newly isolated Kosakonia cowanii strain T6-2

本研究通过整合基因组学与功能性分析,表征了新分离的耐盐促生长植物根际细菌——科萨克尼亚菌(*Kosakonia cowanii*)T6-2株,证明其通过特定的渗透调节物质积累和离子运输机制来缓解盐胁迫,同时增强盐碱农业生态系统中的作物生长和养分有效性。

Estiak Ahmmed, Qingzhen Xiong, Xinyue Yang, Baofu Qin, Hong Xu, Lixin Zhang2026-09-11
🧬 biology

Perfusable Three-Dimensional Polyurethane (PU) Scaffold Platform Promotes Multicellular Tumor Spheroid (MCTS) Formation of U87 Glioblastoma for Tumor Microenvironment Modeling

本研究展示了一种具有仿脑机械性能和互连孔隙的仿生、可灌注三维聚氨酯支架,该支架能够支持 U87 胶质母细胞瘤多细胞肿瘤球的长期形成、活力以及药物响应性生长,用于先进的肿瘤微环境建模和临床前治疗筛选。

Kevin L. Zhang, Rabab Hamzah, Jeffrey Chu, Matthew Duazo, Samuel Kaldas, Robert Griffin, Karrer Alghazali2026-09-11
🧬 biology

Feasibility of a Within-Subject fMRI Design for Eyeblink Conditioning in Future Treatment Studies

本研究表明,用于延迟性眨眼条件反射的被试内 fMRI 设计对于未来的治疗研究是可行的,因为尽管需要考虑会话效应和学习迁移,该设计仍成功地在两场实验会话中于健康受试者身上诱发了具有可比性的行为和神经学习效应。

Dana Reschwamm, Frederik Schlitt-Nguyen, Zsofia Spisak, Friedrich Erdlenbruch, Andreas Thieme, Sönke Konrad, Sillay Aziz (…)2026-09-11