Breed-Dependent IgG Subclass Responses Are Associated with Differential Bm86 Vaccine Efficacy Against Rhipicephalus microplus in Taurine Cattle
This study demonstrates that in taurine cattle, breed-specific differences in IgG subclass profiles, particularly an IgG2-skewed response in Aberdeen Angus rather than total antibody levels, are the primary determinants of differential efficacy against *Rhipicephalus microplus* following Bm86 vaccination.