Optimization of Phycocyanin Production and Purification from Spirulina platensis CCATMU through micronutrient induction: Evaluation of Antioxidant Activity and Biosafety Assessment
This study demonstrates that supplementing *Spirulina platensis* cultivation with 0.1 mg/mL chromium significantly enhances phycocyanin biosynthesis, which, when combined with ultrasound-assisted extraction and stepwise purification, yields high-purity pigment with moderate antioxidant activity and low acute toxicity suitable for large-scale nutraceutical and cosmetic applications.