📄 chemistry

Effects of Tablet Crushing Methods on Solid-State Properties, Dissolution Behavior, and Dispensability of Acetaminophen Tablets

This study demonstrates that different tablet crushing methods significantly alter the solid-state properties, particle characteristics, and dissolution behavior of acetaminophen tablets, with oscillatory ball milling causing the most substantial crystallinity reduction and tablet crushing yielding the finest particles and fastest dissolution despite potential aggregation issues from excessive grinding.

Yayoi Kawano, Tomohiro Tsuchida, Na Rong, Kaoru Hirose, Nobuyuki Natori, Narumi Maida, Satoru Goto, Takehisa Hanawa2026-07-09
📄 chemistry

Predicion of Elastic Properties of Carbon Plastics Obtained by Vacuum Bag Resin Infusion and Direct Prepreg Pressing Technologies

This study compares the elastic properties of carbon fiber composites manufactured via vacuum infusion and prepreg pressing, finding that while theoretical predictions based on Voigt, Halpin-Tsai, and classical laminate theory models align well with experimental bending results, they show significant discrepancies in compression tests.

Artem Filippov, Kirill Pervukhin, Dmitriy Vichuzhanin, Maksim Cvetkov2026-07-09
📄 chemistry

Dichlorotetrazine-Mediated Peptide Cyclodimerization Enables Exponential Expansion and Topological Diversification of Peptide Libraries

This paper reports a serendipitously discovered 3,6-dichloro-1,2,4,5-tetrazine-mediated cascade reaction that enables the one-pot, exponential expansion of linear peptide libraries into diverse bicyclic architectures through selective cyclodimerization, offering a versatile platform for next-generation peptide drug discovery and functionalization.

Kuan Hu, Quan Zuo, Quanshu He, Jie Yan, Ximiao Yang, Hao Tian, Hongyi Huang, Xin Gao, Jieting Shen, Yonghui Hu, Linger L (…)2026-07-09
📄 chemistry

ChemPointNet: A 3D Geometric Deep Learning Framework for Virtual Screening of Potential EGFR Tyrosine Kinase Inhibitors

This study introduces ChemPointNet, a novel 3D geometric deep learning framework that successfully identified and validated 17 highly active EGFR tyrosine kinase inhibitors from the SPECS library through an integrated workflow of virtual screening, molecular docking, enzymatic assays, and molecular dynamics simulations.

Yuepeng Gao, Lingmi Zhao, Sujuan Zhang, Xuecheng Huang, Jie Xia, Pinghua Sun, Xinhui Pan, Wei Zhang2026-07-09
📄 chemistry

Constructing Heterostructure via Calcination-Induced Phase Transformation from α-MnO 2 to Mn 3 O 4 for Enhanced Zinc-Ion Storage

This study reports the fabrication of a three-dimensional α-MnO₂/Mn₃O₄ heterostructure via calcination-induced phase transformation, which enhances zinc-ion storage performance through lattice expansion, increased oxygen vacancies, and a reversible dual-mode charge storage mechanism, resulting in superior specific capacity and cycling stability compared to pristine α-MnO₂.

Yicong Wang, Feizhou Li, Huaming Qian, Xiaohua Pu2026-07-09
📄 chemistry

Photocatalytic GO - TiO₂ - Incorporated TFN Nanofiltration Membranes for Antibiotic Removal from Wastewater

This study demonstrates that optimizing the incorporation of graphene oxide and titanium dioxide into thin-film nanocomposite membranes significantly enhances their performance, achieving high water flux, superior antibiotic rejection (96% for amoxicillin and 94% for ciprofloxacin), and effective photocatalytic degradation (83%) for wastewater treatment.

Getachew Semegn, Firi Ziyad, Wondalem Misganaw, Minbale Aschale2026-07-09
📄 chemistry

Raw Sugarcane Bagasse Hydrochar Outperforms Carbon Nanotubes in Microbial Fuel Cell Power Generation

This study demonstrates that minimally processed raw sugarcane bagasse hydrochar electrodes significantly outperform commercial carbon nanotubes in microbial fuel cell power generation, offering a cost-effective, high-performance, and scalable circular-economy solution for bioelectrochemical systems.

Abdul Azeez Olayiwola Sirajudeen, Kamil Kayode Katibi, Mohamad Suffian Mohamad Annuar, Shaliza Ibrahim, Muhammad Aliyu (…)2026-07-09