📄 Category

chemistry

1676 papers

📄 chemistry

AQbD-Assisted Development and Validation of a Stability-Indicating and Greener HPTLC- Densitometric Method for Simultaneous Determination of Dapagliflozin and Sitagliptin in Pharmaceutical Formulations

This study presents a robust, stability-indicating, and greener HPTLC-densitometric method for the simultaneous determination of dapagliflozin and sitagliptin in pharmaceutical formulations, which was systematically optimized using an Analytical Quality by Design (AQbD) approach and fully validated according to ICH guidelines.

Priyanka Malani, Zeel Shah, Lakshmi Radhika G, Salaj Khare, Kautuk P Shah, Archana Barot, Imtiyaz Bagban, Bansari Patel (…)2026-09-09
📄 chemistry

Dual-Function Molecularly Imprinted Polypyrrole Enables Adhesion-Layer- Free Gold Nanostructures for Selective, Antifouling Dopamine Monitoring during Neuronal Differentiation

This study presents a dual-function molecularly imprinted polypyrrole-coated gold nanostructure sensor that eliminates the need for adhesion layers while providing mechanical stability, antifouling properties, and high selectivity for the direct, long-term electrochemical monitoring of dopamine during neuronal differentiation.

Joon-Ha Park, Yeon-Woo Cho, Min-ji Kang, Eun-Cheol Kwak, Tae-Hyung Kim2026-09-09
📄 chemistry

Impact of Elemental Segregation on Active and Transpassive Corrosion Phenomenology of Additively Manufactured 316L

This study demonstrates that elemental segregation of Cr, Ni, and Mo within the non-equilibrium microstructures of additively manufactured 316L stainless steel, rather than dislocations, governs its active and transpassive corrosion behavior, with optimal processing parameters yielding superior corrosion resistance compared to wrought counterparts.

Timothy Montoya, Duane Macatangay, Robert G. Kelly2026-09-09
📄 chemistry

Synthesis, characterization and antimicrobial activity of novel Pd(II) complexes with athracenylbased Schiff bases

This study reports the synthesis, characterization, and evaluation of novel Pd(II) complexes derived from anthracenyl-based Schiff bases, revealing that the metal complexes exhibit significantly enhanced and broader-spectrum antimicrobial activity against various bacterial and fungal strains compared to their free ligands and commercial antibiotics.

Jelena Poljarević, Ana Kandić, Tamara Petrović, Marija Tanović, Jovana Anđelković, Marija Dimitrijević, Stefan Nikolić (…)2026-09-09
📄 chemistry

Photophysical and Antimicrobial Study of N,N'-Bis(salicylidene)ethylenediamine Schiff Base Metal Complexes (M = Zn(II), Ni(II), Co(II), Cr(II), Fe(III), V(IV), Cu(II), Pd(II))

This study synthesizes and characterizes a series of N,N'-Bis(salicylidene)ethylenediamine Schiff base metal complexes with various transition metals, revealing that metal coordination enhances crystallinity and photoluminescence (notably for Ni and Zn) while significantly improving antimicrobial activity, with Pd and Cu complexes showing the strongest antibacterial and antifungal effects, respectively.

S. R. Khandekar, R. S. Palaspagar, S. R. Kelode2026-09-08
📄 chemistry

Optimization of Baicalin Samples Characterization by MALDI-TOF MS

This study optimizes MALDI-TOF MS parameters, particularly by using low laser intensity to minimize in-source dissociation, to accurately characterize and quantify bioactive flavonoids in *Scutellaria baicalensis* extracts and commercial baicalin samples, achieving highly purified preparations with over 50% baicalin content.

Giuseppina Scalzo, Domenico Carmelo Carbone, Paolo Maria Riccobene, Grazia Maria Letizia Consoli, Daniela Clotilde Zampi (…)2026-09-08
📄 chemistry

Laser-Induced Surface Structuring of Silicon for Enhanced Antibacterial Performance of Silver Thin Films

This study demonstrates that depositing silver thin films on femtosecond laser-induced periodic surface structures (LIPSS) on silicon results in non-conformal growth that significantly enhances antibacterial performance against *E. coli* compared to films on flat substrates.

Lynda Lounis, Barthélemy Aspe, Pierre Birnal, Hervé Rabat, Loïc Gimenez, Arnaud Stolz, Fabienne Brulé-Morabito, Anne-Lis (…)2026-09-08
📄 chemistry

Interfacial Reactions Between Calcium Titanate Investment-Casting Shells and Different Titanium Alloys

This study investigates the interfacial reactions between calcium titanate investment-casting shells and three titanium alloys, revealing that while oxygen enrichment occurs in all cases, the Ti-45Al-2Mn-2Nb alloy exhibits a significantly thinner altered zone due to the formation of a protective aluminum oxide barrier that restricts further oxygen diffusion.

Chongyang Li, Shibing Liu, Hongju Li, Tianyi Liu, Hongyu Liu, Weilong Wang, Weichen Qiu, Hewei Qu2026-09-08