194 papers
Genetics is the fascinating study of how traits are passed down and how our DNA shapes everything from eye color to disease risk. At Gist.Science, we bring you the very latest discoveries in this dynamic field directly from bioRxiv, the leading preprint server for biology. Because these findings appear months before formal publication, staying updated requires sifting through complex data that often feels inaccessible to non-specialists.
To bridge that gap, our team processes every new genetics preprint uploaded to bioRxiv, transforming dense scientific reports into clear, plain-language explanations alongside detailed technical summaries. This dual approach ensures that whether you are a seasoned researcher or simply curious about how genes work, you can grasp the core insights without getting lost in jargon. Below are the latest papers in genetics, curated and simplified for your reading.
This study demonstrates that adult-derived polygenic g scores effectively chart the cognitive development of children, showing minimal predictive power in toddlerhood that increases substantially to explain 12% of variance in early adulthood while also correlating with educational achievement and faster cognitive growth.
This study presents a preliminary 16S rRNA metagenomic analysis of six soil samples from North-Central Argentine agroecosystems, revealing a dominance of copiotrophic bacteria alongside specific oligotrophic taxa and characterizing the abundance of agronomically relevant genera to expand understanding of microbial diversity beyond the Pampas region.
This study presents a unified multi-kernel mixed model that integrates oligogenic and polygenic indirect genetic effects to effectively dissect the genetic architecture of group performance, revealing evidence of intergenotypic competition in woody plants and identifying specific competitive variants in apple trees.
This paper introduces a Bayesian Varying Coefficient Model (BVCM) that successfully deciphers the genetic architecture of time-dependent phenotypic plasticity across diverse species by integrating temporal and genetic multivariate structures, thereby detecting dynamic QTLs and reducing missing heritability compared to traditional time-by-time association methods.
This pilot study demonstrates the high efficiency and utility of a scalable approach for simultaneously tagging 30 essential *C. elegans* genes with three distinct fluorophores, successfully revealing novel expression patterns and subcellular localizations to pave the way for whole-genome proteome tagging.
This study identifies the box H/ACA snoRNP component GAR1 as a critical regulator of lipid homeostasis in *Drosophila* that functions upstream of the insulin signaling pathway by ensuring proper alternative splicing of key metabolic transcripts, thereby linking RNA processing machinery to systemic nutrient sensing and developmental growth.
This study demonstrates that virus-like particles (VLPs) serve as an efficient and versatile delivery system for CRISPR/Cas9 and other genome editing tools in pigs and chickens, overcoming previous delivery challenges and advancing applications in livestock improvement and One Health research.
This study presents the first chromosome-scale reference genome assembly for *Quercus canariensis*, generated using PacBio HiFi reads to produce two high-quality haplotypes with over 98% BUSCO completeness, thereby providing a foundational resource for future genomic and evolutionary research on this understudied white oak species.
By sequencing 21 ancient sheeppox virus genomes from Bronze Age remains and medieval parchments, researchers traced the virus's 3,500-year evolutionary history, revealing its divergence timeline, early gene inactivation events, and its long-standing threat to Eurasian food security.
By integrating microsatellite genotyping, phylogenetic analyses, and geometric morphometrics, this study reveals that *Astyanax* sp. in Colombia's Magdalena basin comprises two distinct cryptic lineages exhibiting significant genetic and phenotypic differentiation, thereby highlighting the need for targeted conservation strategies amidst hydroelectric threats.