13909 papers
This cross-sectional study demonstrates that relying solely on total TSH levels leads to significant overdiagnosis of hypothyroidism due to macro TSH interference, particularly in asymptomatic and pregnant populations, and advocates for macro TSH screening to prevent unnecessary treatment and improve diagnostic accuracy.
This study evaluates turnaround time delays in a New Delhi tertiary care hospital's biochemistry and haematology laboratories, revealing that while the analytical phase constitutes the largest time proportion, significant delays stem from pre- and post-analytical factors such as administrative bottlenecks, specimen transportation, and HIS inefficiencies, necessitating targeted workflow and staffing improvements.
This study demonstrates that an EEG-informed multimodal framework combining FBCSP and GLM effectively mitigates hemodynamic artifacts during ecological upper-limb movements in stroke patients, successfully revealing distinct, stage-associated patterns of cortical reorganization across Brunnstrom recovery stages that conventional methods fail to capture.
This case report describes the successful surgical excision and histopathological confirmation of a rare, giant intramuscular lipoma in the thigh of a 42-year-old man, emphasizing the critical role of detailed imaging in preoperative planning for such deep-seated benign tumors.
This retrospective cohort study of 738 maintenance haemodialysis patients in East China demonstrates that pre-frailty and frailty are independently associated with significantly increased frequencies and costs of all-cause hospitalizations, revealing a clear dose-response relationship that underscores the need for early frailty detection to reduce healthcare burdens.
This multicenter Asian registry study found that preoperative chemoradiotherapy did not significantly improve disease-free or overall survival compared to upfront surgery in patients with early-onset clinical stage II–III rectal cancer who underwent surgical resection.
This study demonstrates that conversion total hip arthroplasty using a cementless monoblock tapered fluted revision stem provides reliable femoral fixation and acceptable functional outcomes for patients with failed proximal femur fracture fixation due to broken cephalomedullary nails, although postoperative functional results are significantly influenced by preoperative ASA grade.
This cross-sectional study of 1,007 Chinese pregnant women found that higher dietary intakes of spermidine and putrescine, but not spermine, were significantly associated with an increased prevalence of gestational diabetes mellitus.
This study demonstrates that in critically ill patients, the spatial QRS-T angle derived from the first ECG is the strongest predictor of 28-day mortality, while new-onset repolarization abnormalities serve as early warning signals for arrhythmias and myocardial injury, establishing whole-cycle ECG dynamics as a comprehensive, actionable monitoring tool for prognosis and pharmacodynamic assessment in the ICU.
A study of 30 parents found that a majority would accept participating in a first-in-human trial of artificial womb technology for 23-week gestational infants, driven by hope for better outcomes, though their willingness depends on transparent communication regarding risks and trial safeguards.