📄 medicine

From Whole-Tooth to Root-Specific Vitality Preservation: Partial Pulpotomy, Full Pulpotomy, and Selective Endodontic Treatment in Mature Permanent Teeth with Symptomatic Irreversible Pulpitis — A Case Series with 12–24 Month Follow-up

This case series demonstrates that a graded, root-specific approach to managing symptomatic irreversible pulpitis in mature multirooted teeth—ranging from partial and full pulpotomy to selective endodontic treatment—can successfully preserve pulp vitality and ensure periapical health in all treated roots over 12–24 months.

Abhijith P P, Rayaz Rasheed, Sapna C Muddappa, Rakesh R Rajan, Prabath Singh V P2026-10-11
📄 medicine

Agreement of Radiographic Parameters Between Digitally Reconstructed Radiographs from Weight-Bearing Cone-Beam CT and Whole-Spine Radiographs

This study demonstrates that digitally reconstructed radiographs generated from weight-bearing cone-beam CT exhibit high agreement and superior interobserver reliability compared to standard whole-spine radiographs for most spinal and pelvic structural parameters, though some discrepancies remain in global balance and specific sagittal curvature measurements.

Xiangyu Nie, Guilin Chen, Jie Wang, Haonan Chen, Jingxi Su, Xiangjie Yin, Lin Xu, Yun Wang, Ruiyao Qin, Shuo Ma, Zhe Zha (…)2026-10-11
📄 medicine

Diversity, Distribution, and Plasmodium falciparum Sporozoite Infectivity of Anopheles Mosquitoes in Flood-Prone Communities of Kasese District, Western Uganda: A Cross- Sectional Household Entomological Study

This cross-sectional study in flood-prone communities of Kasese District, Uganda, reveals a diverse assemblage of Anopheles mosquito species and ongoing low-level Plasmodium falciparum transmission, highlighting the need for targeted vector control interventions in these climate-vulnerable areas.

Rogers Kalyetsi, Kaylin Lewandowski, Ronnie Ndizeye, Raquel Reyes, Mbusa Rapheal, Abel Bwambale, Emmanuel Baguma, Liao H (…)2026-10-11
📄 medicine

The Lived Experience of Chinese Patients With Somatic Symptom Disorder: An Interpretative Phenomenological Analysis

This study utilizes Interpretative Phenomenological Analysis to explore the lived experiences of eight Chinese patients with Somatic Symptom Disorder, revealing that their symptoms stem from a fear of death and an unsafe worldview, and recommending that clinicians address these underlying psychological drivers through empathic validation and cognitive reframing rather than redundant physical investigations.

Yihan Xue, Fazhan Chen2026-10-11
📄 medicine

Metabolic Syndrome and the Risk of Depression and Anxiety: A Prospective Cohort Study

This prospective cohort study of over 316,000 participants demonstrates that metabolic syndrome significantly increases the risk of developing new-onset depression and anxiety through a dose-response relationship, with central obesity and low HDL cholesterol being key drivers and systemic inflammation partially mediating this association.

Siyi Shen, Xinmeng Yao, Qixin Zhang, Ziyi Huang, Jiayu Li, Fei Pan, Yingying Mao, Xian Zhang2026-10-11
📄 medicine

Evaluation of Hospital Preparedness and Response to Trauma Through a Full-Scale Disaster Drill: A Multimethod Study

This multimethod study evaluating a hospital's full-scale trauma disaster drill found that while frontline clinical triage was effective, systemic inefficiencies in communication, command coordination, and resource logistics significantly hindered the overall mass casualty response.

Kripa Maharjan, Aakash Bhandari, Aayush Chaulagain, Shruti Silwal, Mala Deep Upadhaya, Amit Chand2026-10-11
📄 medicine

Cardiopulmonary phenotypes as markers of high risk in patients with COPD in primary care: the MASTER-EPOC study

The MASTER-EPOC study demonstrates that integrating exacerbation profiles with cardiovascular risk in primary care COPD patients reveals clinically distinct phenotypes, including a "hidden-risk" group of non-exacerbators with cardiovascular disease who face significantly higher hospitalization rates and poorer disease control.

Alberto Calderón-Montero, Raul Alonso-Avilés, Ancor Sanz-García, Martínez-Tahoces Sheila, Cristina Millares-López, Mirel (…)2026-10-11
📄 medicine

Endothelium-in hydrodissection (Muraine) versus endothelium-out stripping graft preparation for Descemet Membrane Endothelial Keratoplasty: a prospective two-centre cohort study

This prospective two-centre cohort study found that while the Muraine endothelium-in hydrodissection technique for DMEK offers faster graft unfolding and equivalent early visual and endothelial outcomes compared to the standard endothelium-out method, it is associated with longer dissection times, higher rates of partial tissue loss, increased 6-month endothelial cell loss, and a significantly greater need for rebubbling due to air-only tamponade.

Eduard Pedemonte-Sarrias, Antoni Salvador, José Luis Güell, Irene Sassot, Oscar Gris, José García-Arumí2026-10-11