4372 papers
This study from the Bogalusa Heart Study demonstrates that long-term variability in vascular risk factors (specifically systolic blood pressure and glucose) from childhood to midlife is independently associated with poorer cognitive function, suggesting that early-life stability in these factors is crucial for preserving cognitive health.
This study utilizing causal forest analysis on 15,610 elderly sepsis patients from the MIMIC-IV database reveals that while acute organ dysfunction (SOFA score) is the primary driver of 28-day mortality, the frailty index offers significant incremental prognostic value specifically for patients aged 65–75 and those without acute kidney injury.
This propensity score-matched retrospective study demonstrates that the visual treatment solution (VTS) navigation system significantly improves acetabular cup placement accuracy and reduces leg length discrepancy in primary total hip arthroplasty compared to conventional manual techniques, albeit with a modest increase in operative time.
This retrospective multicenter study demonstrates that topical losartan is a promising adjunctive therapy for improving visual acuity, reducing corneal opacity area, and decreasing corneal density in patients with herpetic corneal scarring over a six-month period.
This multilevel analysis of the 2022 Ghana Demographic and Health Survey reveals that caretaker-reported acute respiratory infection symptoms among children under five are significantly lower in urban areas and the Greater Accra region, while being highest in the Northern, Savannah, and Bono East regions, with no evidence of harm from full vaccination.
This prospective comparative study of elderly patients with unstable intertrochanteric fractures found that while proximal femoral nailing offers shorter operative time and less blood loss, cemented calcar-replacement hemiarthroplasty provides a reliable alternative with earlier mobilization, fewer immobilization-related complications, and reduced mechanical failure, ultimately resulting in comparable long-term functional outcomes.
This mixed-methods study reveals that while geriatric nurse specialists' training transfer is positively driven by their advanced practice competencies, it is significantly constrained by organizational barriers such as resource shortages, role ambiguity, and a lack of incentives, necessitating targeted policy and systemic improvements to fully realize their professional value.
This study developed and validated a clinically translatable risk score using seven routine blood markers, age, and sex to accurately predict five-year mortality in community-dwelling older Indians, addressing a critical gap in prognostic tools for this under-studied South Asian population.
This multi-institutional Asian cohort study of 1,021 patients demonstrates that type A aortic dissection with malperfusion carries significantly higher short- and long-term mortality risks compared to cases without malperfusion, with cerebral malperfusion identified as a critical predictor of surgical death that should be integrated into risk stratification models.
This case report describes a 4-year-old boy whose periurethral urinoma, caused by a congenital anterior urethral diverticulum, initially mimicked scrotal cellulitis and required advanced imaging and surgical intervention for correct diagnosis and treatment after failing standard antibiotic therapy.