4378 papers
This pilot study demonstrates that a low-cost, simulation-based curriculum effectively improves general surgery residents' confidence and perceived educational value in managing common benign anorectal conditions, thereby helping to bridge early technical skill gaps despite not guaranteeing immediate procedural mastery.
This case report describes a rare instance of Stevens-Johnson syndrome triggered by ciprofloxacin and tinidazole in a 65-year-old woman, highlighting the critical importance of early drug discontinuation and supportive care for successful patient recovery.
This Italian case report describes the successful diagnosis and treatment of a 67-year-old man with a mixed *Plasmodium falciparum* and *Plasmodium ovale curtisi* malaria infection, highlighting the critical role of integrating microscopy, rapid antigen testing, and molecular assays to accurately identify complex co-infections in non-endemic settings.
This study utilizes a deterministic compartmental model fitted to routine data from six Nigerian states to demonstrate that while Seasonal Malaria Chemoprevention (SMC) significantly reduces malaria morbidity beyond its targeted population, its overall effectiveness is critically dependent on underlying vector dynamics, necessitating integration with complementary vector control interventions for sustained impact.
This hybrid type 2 cluster-randomized trial demonstrates that a "Prepare for Sustainment" strategy, combining initial training with ongoing coach supervision supported by external consultants, is more effective than usual practices in maintaining high process fidelity and improving student behavioral engagement and mental health outcomes for evidence-based programs in urban elementary schools.
This study demonstrates that quantitative synthetic MRI (SyMRI) parameters, particularly when used in a combined diagnostic approach, provide objective and enhanced predictive value for both the diagnosis and severity stratification of neonatal hyperbilirubinemia compared to conventional imaging.
This cross-sectional study of MBBS students in Pokhara, Nepal, reveals that while strict burnout affects 12.1% of students, nearly 90% exhibit at least one burnout dimension, with the highest prevalence occurring in pre-clinical years and a strong association found between maladaptive coping strategies and burnout symptoms.
This retrospective study of 40 critically ill Spanish children with thrombotic microangiopathy treated with complement inhibitors reveals that while half had suspected complement-mediated HUS, the other half received off-label therapy for other subtypes, with non-CM-HUS patients experiencing significantly later treatment initiation, more severe extrarenal manifestations, longer PICU stays, and higher rates of discharge hypertension.
This case-control study demonstrates that while elevated oxidative stress markers distinguish glioma patients from healthy controls, serum YKL-40 levels uniquely correlate with tumor grade, suggesting its potential as a biomarker for differentiating between low- and high-grade gliomas.
While bioelectrical impedance analysis (BIA) demonstrates strong correlation and consistency with dual-energy X-ray absorptiometry (DXA) for assessing body composition in Parkinson's disease, its systematic underestimation of lean mass and wide limits of agreement preclude its use as a direct substitute for DXA in individual clinical settings, though it remains valuable for population-level screening.