📄 medicine

Clinical traits and Associated risk Factors of Hypertension: A Community-Based Study in different wards of Dhangadhi Sub Municipality Kailali, Nepal

This community-based cross-sectional study conducted in Dhangadhi, Nepal, between October 2024 and February 2025, found a hypertension prevalence of 31.35% among 545 participants and identified significant associations between the condition and gender and smoking, highlighting the need for community-based preventive measures.

Bikash Rijal, Aashwin Joshi, Ashok Pandey2026-07-03
📄 medicine

Quality Improvement Cycle in Patient-Centered Care for Oncology Patients in an Outpatient Service

This quasi-experimental study demonstrates that implementing a quality improvement cycle in an outpatient oncology service in Brazil's Northeast significantly reduced nonconformities in care for patients with low Palliative Performance Scale scores, while highlighting the need to adapt palliative care practices to local cultural contexts.

Albertina Proença Rodrigues Alves, Michel Siqueira da Silva, Susana Cecagno, Vilani Medeiros Araújo Nunes2026-07-03
📄 medicine

Silymarin extract outperforms its nanomodified form in inhibiting colon cancer cell proliferation

This study demonstrates that native Silymarin extract exhibits superior anticancer efficacy and selectivity against colon cancer cells compared to its nanomodified form by inhibiting MAPK proliferation pathways and activating P53-mediated apoptosis while sparing normal epithelial cells.

Naglaa Fatahy, Khalid Bassiouny, Mahmoud Al-Saman, Aysam M. Fayed, Ahmed M. Tabl, Amal A. Abd-El-Aziz, Hany Khalil2026-07-03
📄 medicine

Reporting Quality of Prosthodontics-Related Systematic Reviews in SCI-E Indexed Journals: A PRISMA-Based Evaluation Short Title: Reporting Quality of Prosthodontics-Related Systematic Reviews

This study evaluated the reporting quality of 40 prosthodontics-related systematic reviews published in SCI-E journals between 2010 and 2019 using the PRISMA checklist, finding that while quality has significantly improved over time with publication year as the only significant predictor, important deficiencies in adherence to reporting standards remain.

Nigar Baghirova, Şeyma Aliye Kara, Banu Çakır, Kıvanç Akça2026-07-03
📄 medicine

The relationship between compassion fatigue and professional identity among vocational undergraduate nursing interns: a cross-section network analysis

This cross-sectional network analysis of 271 vocational undergraduate nursing interns reveals that work-related disappointment and professional happiness are central to compassion fatigue and professional identity respectively, while competence utilization serves as the critical bridge node linking these constructs through negative associations.

Bingyue Zhao, Huiling Yang, Mengmeng Su, Xiaoshuang Yin2026-07-03
📄 medicine

Aconitine accidental poisoning: two case reports and literature review

This paper reports two cases of fatal and non-fatal aconitine poisoning resulting from the ingestion of improperly processed Chinese herbal medicines, highlighting the severe cardiotoxic and neurotoxic risks associated with *Aconitum* species and emphasizing the urgent need for enhanced public awareness and rational clinical use to prevent future adverse events.

Qian Zhao, Lei Wang, Feng Zeng, Xue-bo Jiang, Yan-xia Shao2026-07-03
📄 medicine

Inclusive Design for Digital Health Interventions for Older Adults: A Comparative Analysis of Literature, Expert, and User Perspectives

This study triangulates literature, expert, and older adult perspectives to demonstrate that inclusive design for digital health interventions targeting older adults must extend beyond usability and accessibility to encompass emotional, ethical, and systemic dimensions, with a strong consensus on the foundational importance of personalization and ongoing user support.

Kerstin Denecke, Carolyn Petersen, Emilene Zitkus, Lana Cvijic, Beatrice Kaufmann2026-07-03
📄 medicine

Agreement of artificial intelligence equipped stethoscopes with known echocardiogram results in screening emergency department patients for audible murmurs

This study demonstrates that an AI-equipped digital stethoscope achieves higher sensitivity than blinded human reviewers in detecting audible heart murmurs in emergency department patients, although both methods struggle with inaudible structural heart disease.

Matthew Hysell, Zara Chaudhry, Monique Luna, Rachelle Pichot, Zachary Heeringa, Ahn-Taun Tong, Michelino Mancini2026-07-03