📄 medicine

Maternal obesity and offspring adiposity trajectories during early childhood: a longitudinal study from the PONCH cohort

This longitudinal study of the PONCH cohort reveals that children born to mothers with obesity exhibit progressively higher adiposity throughout preschool age compared to those born to mothers with normal weight or gestational diabetes, suggesting maternal obesity is a more sustained determinant of early childhood adiposity development than gestational diabetes.

Sebastian Åberg, Ulrika Andersson-Hall, Emilia Kristiansson, Agneta Holmäng2026-07-05
📄 medicine

Budget impact analysis of Gastric Alimetry® in patients with chronic gastric symptoms in the United Kingdom National Health Service

A budget impact analysis suggests that integrating the non-invasive Gastric Alimetry® system into the UK NHS for diagnosing and managing chronic gastric symptoms could generate nearly £50 million in net cost savings over 5.4 years by significantly reducing hospital admissions, emergency visits, and other healthcare resource utilization compared to the current standard of care.

Mikaela Law, Eva Fuchs, Natalia Zarate-Lopez, Charlotte Daker, Asma Fikree, Christopher N. Andrews2026-07-05
📄 medicine

Astigmatism Shift in Low-Astigmatism Myopic Children Wearing Highly Aspherical Lenslets: A Self- Controlled Cohort Study

This self-controlled cohort study reveals that highly aspherical lenslets (HAL) accelerate astigmatism progression exclusively in myopic children with low baseline astigmatism by disrupting the compensatory balance between corneal and internal astigmatism, without compromising the treatment's core efficacy in controlling axial elongation.

Kaihuai Yu, Yuejia Peng, Jin Zhang, Haoqi Lan, Qiaolan Zheng, Jie Chen, Wuhe Chen2026-07-05
📄 medicine

Investigation of Plasmodium Species in Donated Stored Blood Units at Ndola Teaching Hospital, Ndola, Copperbelt Province, Zambia

This study reveals that 8% of ready-to-transfuse blood units at Ndola Teaching Hospital in Zambia contain *Plasmodium* parasites, predominantly *P. falciparum*, highlighting a critical, unmonitored risk of transfusion-transmitted malaria that necessitates the inclusion of malaria screening in national blood safety protocols.

Patrick Loti, Frank Chisulo K., Agness Chama, Alick Mwambungu, Karen Chanda, Mazuba Banda2026-07-05
📄 medicine

Clinical Validation of Orthodontic Oral Health Literacy and Behavior Tools (OHL-Ortho & OHB): A Cross-Sectional Assessment Using CPITN, OHI-S and Objective Knowledge Measures

This study provides the first clinical validation of the newly developed OHL-Ortho and OHB instruments, demonstrating their strong reliability and significant ability to predict factual knowledge, oral hygiene behaviors, and clinical periodontal outcomes in adult patients undergoing fixed orthodontic treatment.

Muhammad Raif Ilyas, Syed Muhammad Ali Gilani, Muhammad Mughni, Mubassar Fida, Rashna Hoshang Sukhia2026-07-05
📄 medicine

Reliability and Clinical Accuracy of ChatGPT in Post-FESS Counselling: A Multi-Reviewer Evaluation.

This study evaluates ChatGPT's performance in generating postoperative FESS counseling, finding that while it offers acceptable reliability for standardized guidance with high inter-rater agreement on appropriateness, it exhibits limitations in contextual accuracy and readability that necessitate clinician oversight.

PARAMITA DEBNATH, MISBAHUL HAQUE, PRAKRITI SAMADDAR, NEHA YADAV2026-07-05
📄 medicine

Biofeedback using electrical impedance tomography during inhalation therapy for chronic obstructive lung disease – a pilot study

This pilot study demonstrates that while biofeedback-guided inhalation using electrical impedance tomography did not improve obstructive lung parameters (FEV1) in COPD patients, it significantly reduced hyperinflation (FRC) compared to standard inhalation, suggesting potential benefits for inhalation technique and lung volume management.

Svenja Stolz, Rosa Meyer, Torben Rixecker, Robert Bals, Philipp M. Lepper, André Becker2026-07-05
📄 medicine

Association between atherogenic index of plasma and mortality of patients with sepsis: Evidence from a large population-based study based on the MIMIC-IV database and EICU-CRD database

This large population-based study utilizing MIMIC-IV and EICU-CRD databases reveals that a higher atherogenic index of plasma (AIP) is independently and non-linearly associated with increased 168-hour mortality in sepsis patients, with lactate metabolism and organ dysfunction serving as key mediating mechanisms.

Juan Wang, Yanfang Shang, Limeng Zhang, Yan Wang, Haibo Ge2026-07-05