5613 papers
This study demonstrates that smoking status stratifies distinct Th1/Th2 immune phenotypes in pre-COPD high-risk individuals, revealing quantile-specific blood biomarkers that detect early immune dysregulation missed by conventional methods and could serve as cost-effective screening tools in primary care.
This study developed and clinically validated a deep learning framework, specifically a Swin-UNETR model, which achieves high-accuracy automated segmentation of maxillary edentulous regions in CBCT images, significantly reducing implant planning time and improving reproducibility compared to conventional workflows.
Although the NIH RECOVER-Adult cohort successfully enrolled a large and diverse population through targeted community outreach, the study found that retaining sociodemographically representative participants, particularly those from minoritized and vulnerable groups, proved more challenging than initial enrollment, underscoring the need for innovative retention strategies in post-pandemic research.
This randomized crossover study demonstrates that acute inhalation of heated tobacco products by healthy young individuals rapidly elevates circulating extracellular vesicles expressing biomarkers associated with pulmonary injury, cellular stress, and inflammation, suggesting these products may impair lung health and trigger pro-thrombotic cascades.
This retrospective cohort study of 390 patients with severe aortic stenosis in the Ecuadorian Andean Highlands found a 12.1% prevalence of significant coronary artery disease, identifying the coronary calcium score as the most effective noninvasive diagnostic tool and the low-flow/low-gradient echocardiographic pattern as the strongest phenotypic predictor, while noting that the local prevalence is lower than in European and North American registries.
This study developed and validated a 15-item electronic questionnaire to assess orthodontists' awareness and clinical practices regarding maxillary molar distalization, revealing that most practitioners utilize the technique primarily for Class II malocclusions with a preference for skeletally anchored devices while emphasizing the critical role of three-dimensional imaging to prevent bone damage.
This case report describes the first use of personalized prophylactic bacteriophage therapy to successfully suppress extensively drug-resistant Pseudomonas aeruginosa in a cystic fibrosis patient following lung retransplantation, although the patient ultimately died from unrelated multiorgan failure.
This study of workplaces in Chongqing, China, reveals that relying solely on occupational exposure limit compliance significantly underestimates health risks from silica dust, as nearly 40% of compliant positions were still classified as high or very high risk by semi-quantitative assessment, suggesting that combining both methods is essential for effective silicosis prevention.
This study demonstrates that machine learning models, particularly Support Vector Regression and tree-based ensembles, can accurately predict short-term blood glucose levels for both Type 1 and Type 2 diabetes patients while leveraging SHAP and LIME techniques to provide transparent, interpretable insights that support clinical decision-making.
This cross-sectional study of healthcare professionals in South India reveals moderate awareness and highly positive attitudes toward 3D bioprinting, despite a significant lack of formal educational exposure, suggesting an urgent need for educational initiatives to facilitate the technology's future adoption.