5683 papers
This multicenter cross-sectional study of over 8,000 Chinese patients with central nervous system disorders reveals that residing in higher-tier cities independently predicts more severe disability, a macro-environmental risk that is significantly exacerbated for low socioeconomic status individuals but buffered for those with high socioeconomic status.
This retrospective comparative study demonstrates that combining intramedullary nailing with plate fixation for femoral shaft nonunion significantly shortens the time to authorized and effective full weight-bearing compared to isolated exchange nailing, without compromising union rates or increasing septic complications.
This single-centre study of 85 patients with Nagashima-type palmoplantar keratoderma characterizes the disease's clinical heterogeneity, including its association with atopic dermatitis and renal abnormalities, and expands the known genotypic spectrum of *SERPINB7* while identifying specific demographic and genetic patterns.
This randomized controlled trial demonstrates that daily docosahexaenoic acid (DHA) supplementation significantly improves cognitive function in older Chinese adults with mild cognitive impairment, an effect that is partially mediated by the modulation of ferroptosis-related biomarkers.
This study proposes a simplified two-step screening process for dyslexia in Indian primary school children, validating the web-based Dynaread tool as an effective, sensitive, and time-efficient method for large-scale early detection with an estimated prevalence of 8.33%.
This study reveals that long-term follow-up adherence among high-myopia patients after ICL implantation declines sharply over time, leading to delayed detection of sight-threatening complications, and highlights that improving patient knowledge and attitudes through targeted education is crucial for enhancing monitoring and preventing vision loss.
This study demonstrates that *Origanum* essential oil significantly reduces *Blastocystis* cyst shedding, alleviates oxidative stress and inflammation, and restores intestinal tissue architecture in experimentally infected mice, showing therapeutic efficacy comparable to or exceeding that of the standard drug nitazoxanide.
This study analyzes NHANES data from 1999–2018 to reveal that the triglyceride-glucose (TyG) index exhibits a threshold effect on mortality among cancer survivors, with risks decreasing below specific levels (8.24–8.39) but increasing for cardiovascular and diabetes-related deaths at higher levels, suggesting it is a valuable prognostic marker for targeted interventions.
This retrospective study of maintenance hemodialysis patients demonstrates that albumin variability, rather than absolute values, is the strongest independent biological marker associated with erythropoiesis-stimulating agent (ESA) hyporesponsiveness, suggesting that monitoring albumin instability could help identify patients at risk for deteriorating ESA efficacy.
This cross-sectional study of 300 young adults demonstrates that sleep quality and perceived stress significantly mediate the relationship between physical activity and cardiorespiratory fitness, both independently and through a serial pathway.