medicine papers | Gist.Science

Albumin Variability and Biological Instability Associated With ESA Hyporesponsiveness in Maintenance Hemodialysis Patients

This retrospective study of maintenance hemodialysis patients demonstrates that albumin variability, rather than absolute values, is the strongest independent biological marker associated with erythropoiesis-stimulating agent (ESA) hyporesponsiveness, suggesting that monitoring albumin instability could help identify patients at risk for deteriorating ESA efficacy.

Yukinobu Ikegishi2026-07-02

📄 medicine

A mediation model of physical activity levels and cardiorespiratory fitness: The role of sleep quality and stress

This cross-sectional study of 300 young adults demonstrates that sleep quality and perceived stress significantly mediate the relationship between physical activity and cardiorespiratory fitness, both independently and through a serial pathway.

Hemlata Vats, Richa Hirendra Rai, Saima Zaki, Ankita Dey2026-07-02

📄 medicine

A novel homozygous GINS2 variant with Meier–Gorlin syndrome with clinical and epigenetic characterisation

This study reports a second patient with homozygous GINS2 variants causing Meier–Gorlin syndrome, expanding the clinical phenotype to include craniosynostosis and NK cell deficiency while revealing epigenetic alterations linked to skeletal and craniofacial development.

Pauline Marzin, Arthur Bellanger, Giovanna Paternoster, Klervie Loiselet, Nicolas Doldi, Matthieu Defrance, Capucine Pic (…)2026-07-02

📄 medicine

Pre-school vision screening by teachers in Enugu State, Nigeria: accuracy and willingness to conduct screening

While pre-school teachers in Enugu State, Nigeria, demonstrated high willingness to conduct vision screening for children aged 3–5 years, their sensitivity in accurately detecting visual impairment was low despite high specificity.

Chinonso Nnagbo, Nnenma Udeh, Ifeoma Ezegwui, Azuka Onwuasoanya, Adaobi Akunne2026-07-02

📄 medicine

Pediatric Cardiac Masses: Clinical Characteristics and Long-Term Outcomes From a Two-Decade Single-Center Experience

This two-decade single-center retrospective study of 22 pediatric patients highlights the substantial clinical and biological heterogeneity of cardiac masses, demonstrating that while rhabdomyomas are often associated with tuberous sclerosis and tend to regress spontaneously, non-rhabdomyoma lesions exhibit greater pathological diversity and more frequently require surgical intervention.

Şeyma Şebnem Ön, Eser Doğan, Zülal Ülger Tutar, Burcu Büşra Acar Alkan, Meral Yılmaz, Hakan Kurt, Burcugül Karasulu Beci (…)2026-07-02

📄 medicine

Emergency department visits in Stockholm – a projection ahead

Using historical data and population forecasts, this study projects that emergency department visits in Stockholm will rise substantially by 2035, driven primarily by rapid population ageing among adults aged 65 and older, necessitating strengthened geriatric-adapted care and improved coordination across healthcare levels.

Clara Brune, Robert Thiesmeier, Nicola Orsini, Ann Liljas2026-07-02

📄 medicine

The Effect of Obesity on the Coccoid Form Transformation of Helicobacter pylori and Its Relationship with Gastric Inflammation Pattern: A Retrospective Comparative Study

This retrospective study demonstrates that obesity, particularly severe obesity, is a strong independent predictor of *Helicobacter pylori* transformation into the coccoid form and increased crypt colonization, suggesting a need for tailored diagnostic and eradication strategies in obese patients.

Burcu SANAL YILMAZ, Sibel ACAT2026-07-02

📄 medicine

Partial Occlusion Device - A Novel 3D-Printed Tool for Microsurgical Anastomosis Revision

This study introduces a novel 3D-printed Partial Occlusion Device (POD) that serves as a stable, reusable, and fiber-free alternative to cotton-tip applicators for microsurgical anastomosis revision, demonstrating comparable efficacy and safety while offering surgeons improved stability and control in a rat femoral artery model.

Yuzhu Huang, Abraham Joshua Johnson, Jonas Zhao, Shahabeddin Yazdanpanah, Elan Shukhmakher, Omer Bilal, Hui Zhang, Tina (…)2026-07-02

📄 medicine

Actinotignum-associated prosthetic aortic valve infective endocarditis complicated by postoperative mixed shock and dialysis-dependent acute kidney injury: a case report

This case report describes a rare instance of *Actinotignum sanguinis*-associated prosthetic aortic valve infective endocarditis in a urologically compromised elderly man, highlighting the diagnostic challenges of slow-growing anaerobes, the necessity of early surgical intervention despite pending microbiological confirmation, and the complex management of postoperative mixed shock leading to patient recovery.

Norihiro Sakai, Aya Seki, Tomohiro Michino2026-07-02

📄 medicine

Low-grade Pancreatic Intraepithelial Neoplasia Mimicking Branch-Duct IPMN in a Patient with Long-standing Systemic Lupus Erythematosus: A Case Report

This case report describes a rare instance of low-grade pancreatic intraepithelial neoplasia mimicking a branch-duct IPMN in a patient with long-standing systemic lupus erythematosus, highlighting the diagnostic limitations of conventional imaging and the severe, life-threatening postoperative complications arising from surgery in immunosuppressed patients.

YuXiao Wang, FuHong Li, Meng Zhu, ZhiRen Xu, Kun Su, XiaWei Yang, Tao Wu2026-07-02

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