6270 papers
Based on a 2024 analysis of over 450,000 U.S. adults, depression is an independent predictor of cost-related medication nonadherence, doubling the odds of missing prescribed drugs due to cost even after adjusting for socioeconomic factors, with income and insurance status emerging as the strongest additional drivers of this disparity.
This paper examines the growing public health issue of nomophobia through an Ayurvedic lens, proposing that integrating traditional holistic practices like Sattvajaya Chikitsa and Rasayana with modern interventions offers a sustainable and culturally acceptable strategy for managing digital addiction and restoring mental balance.
This retrospective cohort study of over 5,000 traffic crash patients in Taiwan reveals that geographic administrative boundaries (specifically New Taipei City versus Taipei City) serve as a potent independent predictor of major trauma severity, even after controlling for physiological status, thereby highlighting the need for region-specific triage protocols that prioritize location and age over traditional physiological triggers.
This study of the SCAN cohort demonstrates that while polygenic risk scores offer modest incremental value for stratifying cancer risk in patients with non-specific symptoms, they show strong, consistent associations with various autoimmune diseases, suggesting a more immediate role for PRS integration in autoimmune diagnostics compared to cancer screening.
This study found that fixed-frame and handheld dynamometers show only moderate to weak correlations in assessing isometric neck strength among female rugby players, indicating that these testing protocols should not be used interchangeably and that a single system should be consistently applied for longitudinal monitoring.
This systematic review and meta-analysis indicates that while most observational studies report a negative association between higher BMI and sexual function in postmenopausal women, the limited meta-analytic evidence does not support a significant pooled effect, suggesting that BMI may not be an independent causal factor.
This study demonstrates that machine learning models using real-world data from the myCOPD digital platform can effectively predict COPD exacerbations with improved precision over previous models, though adding wrist-worn step-count data provided no significant additional value.
This dual-cohort retrospective study demonstrates that the early lactate-to-albumin ratio is an independent predictor of 28-day all-cause mortality in patients with sepsis-associated encephalopathy, suggesting its utility as a valuable biomarker for clinical risk stratification.
A cross-sectional screening of 3,582 Indian long-distance heavy vehicle drivers under the SCOPE initiative revealed a high prevalence of oral potentially malignant disorders, particularly white lesions, which are strongly associated with tobacco use and low health awareness, underscoring the urgent need for targeted screening and intervention strategies for this vulnerable population.
This study demonstrates that elevated baseline serum full-length glypican-3 (FL-GPC3) levels serve as an independent negative prognostic biomarker for disease control, progression-free survival, and overall survival in patients with unresectable hepatocellular carcinoma treated with atezolizumab and bevacizumab.