📄 medicine

Aortic Bifurcation Injury Following Blunt Trauma Presenting as Bilateral Lower Limb Ischemia: A Case Report

This case report describes a fatal outcome in a 57-year-old male with blunt aortic bifurcation injury and bilateral lower limb ischemia, highlighting that despite urgent surgical intervention and amputation, severe reperfusion injury and multiorgan dysfunction syndrome led to death, underscoring the high mortality associated with such rare, complex trauma.

S Sakashan, Dayas M, Andrew Nishanthan, Vinojan Satchithanantham2026-06-28
📄 medicine

Investigating the genetic material sources of abnormal prokaryotes formed by different in vitro fertilization methods

This retrospective study comparing short-term and conventional IVF methods reveals that while short-term IVF yields lower fertilization and blastocyst rates with a higher incidence of 3PN embryos, the majority of these abnormal 3PN cases result from paternal genetic errors rather than maternal ones, and notably, not all 3PN embryos exhibit chromosomal abnormalities.

Jing Chen, Hui Cao, Zhouyang Zhao, Chenchen Wang, Zhengyao Wang, Jinxiang Wu2026-06-28
📄 medicine

Identification of high-impact chronic pain among cancer survivors: a cross-sectional study using the Graded Chronic Pain Scale framework

This cross-sectional study demonstrates that the Graded Chronic Pain Scale–Revised effectively identifies high-impact chronic pain in cancer survivors, revealing that while these patients exhibit lower pain intensity and catastrophizing than non-cancer counterparts, they experience significant disability and psychological distress that necessitate targeted support.

Julie Roed Jespersen, Henrik Bjarke Vaegter, Caroline Matilde Elnegaard, Lene Jarlbaek2026-06-28
📄 medicine

Dynamic Changes in Coronary Blood Flow During Laparoscopic Cholecystectomy and Its Predictive Value for Postoperative Cardiovascular Complications: A Retrospective Study Based on Transesophageal Echocardiography

This retrospective study utilizing transesophageal echocardiography reveals that carbon dioxide pneumoperitoneum during laparoscopic cholecystectomy causes a significant, delayed-recovery reduction in coronary blood flow, where a maximum intraoperative decrease exceeding 28% serves as an independent predictor for postoperative cardiovascular complications, thereby supporting the development of a combined prediction model for early risk stratification.

Zhongchuan Tian, Zhongqiu Niu, Jing Cen2026-06-28
📄 medicine

Preliminary Study on Differences in Systemic Immune-Inflammation Index and Its Prognostic Correlation in Synovial Sarcoma

This retrospective study of 37 synovial sarcoma patients demonstrates that the systemic immune-inflammation index (SII) is significantly associated with tumor subtype, size, and prognosis, suggesting its potential utility in reducing misdiagnosis of small lesions and guiding treatment planning for high-risk patients.

Zhou Yang, Yan Wen, Chen Liqin, Zhu Yan, Wei Lijie, Huang Yumin2026-06-28
📄 medicine

A Rare Entrapment of Temporary Pacing Wire During Transcatheter Mitral Valve-in-Valve Procedure

This case report describes the successful conservative management of a rare temporary pacing wire entrapment during a transcatheter mitral valve-in-valve procedure via wire transection and burial, highlighting the importance of vigilant real-time monitoring and demonstrating that non-extraction strategies can yield favorable long-term outcomes.

Jiabo Shen, Weifang Zeng, Kaidong Cen, Hengdong Li2026-06-28
📄 medicine

Seasonal Patterns and Treatment Outcomes of Severe Acute Malnutrition in Children in Aden, Yemen: A Facility-Based Study from Two Therapeutic Feeding Centers

This retrospective facility-based study in Aden, Yemen, analyzed 1,003 children with severe acute malnutrition admitted in 2024, revealing that while treatment outcomes met international standards and admissions followed distinct seasonal peaks, the volume of admissions was not significantly associated with recovery rates.

Mohamed Salem Baazab, Giovanni Messina, Rita Polito2026-06-28
📄 medicine

Prediction of delayed inpatient antidepressant initiation after the first 24 hours of hospital admission using early electronic health record data: a MIMIC-IV v3.1 landmark prediction study

This study developed and internally validated a landmark prediction model using early structured electronic health record data from the MIMIC-IV database, demonstrating that a boosted-tree algorithm can modestly but meaningfully predict delayed inpatient antidepressant initiation after the first 24 hours of hospital admission, though the model currently serves as a research tool rather than a deployable clinical system.

Hung-Min Huang, Chun-Shun Lu, Geng-Wei Chang2026-06-28