6374 papers
This cross-sectional study conducted in Western India from 2024 to 2025 analyzed 6,068 extrapulmonary tuberculosis samples and found a 16.43% molecular positivity rate with a 6.11% drug resistance prevalence dominated by rifampicin resistance, underscoring the critical need for universal drug susceptibility testing and enhanced surveillance.
This study developed and validated a noninvasive AI model integrating DCE-MRI and clinicopathologic features that outperforms traditional methods in predicting recurrence risk and personalizing treatment for early-stage HR+/HER2− breast cancer.
This case report describes a 7-year-old girl with a novel homozygous HSD3B7 frameshift variant who presented with a rare, late-onset, malabsorption-dominant phenotype of congenital bile acid synthesis disorder type 1 accompanied by renal microcysts, highlighting the critical need to consider urinary bile acid analysis in children with unexplained malabsorption regardless of neonatal history to enable early, disease-modifying treatment.
This cross-sectional study in Dara Malo district, Southern Ethiopia, found a household-level prevalence of 5.11% for parasitologically confirmed cutaneous leishmaniasis and identified significant deficiencies in community knowledge, attitudes, and preventive practices, particularly among males, those with lower education and income, and farming households.
In a cross-sectional analysis of the Rakai Community Cohort Study in Uganda, HIV serostatus was not found to be significantly associated with diagnosed diabetes, whereas older age, higher BMI, higher socioeconomic status, and residence in a fishing community were identified as significant independent risk factors.
A double-blind, cluster-randomized controlled trial demonstrated that repeated use of a novel hand sanitizer with sustained antimicrobial activity significantly reduced the incidence of upper respiratory symptoms and work restrictions compared to a conventional ethanol-based sanitizer over a 72-day winter period.
This multi-provincial cross-sectional study in the Democratic Republic of Congo reveals that nearly 19% of tuberculosis patients have undiagnosed hyperglycemia, with age, specific geographic locations, family history, hypertension, comorbidities, and multidrug-resistant tuberculosis identified as key independent determinants, thereby supporting the integration of systematic diabetes screening into TB programs.
Analysis of the Korean Primary Liver Cancer Registry reveals that initial curative-intent therapies are associated with longer intervals before subsequent treatment and independently predict improved overall survival in hepatocellular carcinoma patients across various tumor stages and liver function classes.
This prospective study demonstrates that aerosolized [18F]NaF PET/CT effectively quantifies significantly reduced regional deposition and mucociliary-dominant early clearance in bronchiectatic lungs compared to healthy tissue, establishing 0 minutes as the optimal time point for assessing aerosol delivery.
This mixed-methods randomized controlled trial demonstrates that a Knowledge, Attitude, and Practice (KAP)-based health education programme for parents of adolescents with fixed orthodontic appliances significantly improves parental health literacy, enhances adolescent treatment compliance, and optimizes periodontal outcomes compared to routine care.