📄 medicine

Open Arthrolysis for Severe Elbow Stiffness Secondary to Primary Elbow Osteoarthritis: A Retrospective Case Series of 60 Patients

This retrospective study of 60 patients demonstrates that open arthrolysis with osteocapsular debridement and concomitant ulnar nerve transposition provides significant short-term improvements in range of motion, pain, and function for severe elbow stiffness secondary to primary osteoarthritis, with a favorable safety profile.

Gang Fu, Shen’ao Wang, Renbin Li, Xiayu Huang, Binbin Jin, Qin Li, Fengfei Lin2026-06-28
📄 medicine

Evaluating Humanitarian Health Interventions in Armed Conflict through Open Official Data: Evidence from Ukraine

This study demonstrates that analyzing open official data from Ukraine's National Health Service provides an objective, evidence-based method for evaluating the impact of humanitarian health interventions in armed conflict, revealing that while clinical mortality rates remained statistically unchanged, the interventions significantly enhanced institutional financial resilience and emergency care capacity in Kharkiv hospitals.

Viacheslav Kondratiuk, Anna Kovalenko, Khrystyna Chaika2026-06-28
📄 medicine

Microbiological Profile of Corneal Ulcers in Patients Who Consulted an Ophthalmological Center in Cartagena (2025)

This prospective study of 40 patients in Cartagena (2024–2025) reveals that infectious corneal ulcers are predominantly fungal in etiology, often associated with vegetative trauma, and characterized by low antimicrobial resistance, underscoring the need for empirical antifungal coverage and localized diagnostic strategies to improve clinical outcomes.

Diana Becerra Becerra, Liliana Hoyos Córdoba2026-06-28
📄 medicine

Diagnostic accuracy of cerebrospinal fluid cytochemical analysis to optimize the use of the FilmArray Meningitis/Encephalitis panel in immunocompetent and immunocompromised patients

This study demonstrates that applying a combined clinical decision rule requiring cerebrospinal fluid pleocytosis (>10 leukocytes/mm³) or elevated protein (>50 mg/dL) to guide the use of the FilmArray Meningitis/Encephalitis panel can significantly improve diagnostic yield by 55.4% while reducing unnecessary testing by 40.1% in both immunocompetent and immunocompromised patients.

Juan Felipe Morantes Rubiano, Laura Restrepo Álvarez, Andrea Mazo Cañola, Juan Pablo Villa Franco, Santiago León Atehort (…)2026-06-28
📄 medicine

[18F]-FAPI-42 versus [18F]-FDG in detecting viable tumors of moderately to poorly differentiated hepatocellular carcinoma

In a retrospective study of 35 patients with moderately to poorly differentiated hepatocellular carcinoma, [18F]-FAPI-42 PET/CT demonstrated significantly superior detection rates for viable tumors compared to [18F]-FDG PET/CT, particularly for intrahepatic lesions and distant metastases to the peritoneum, lung, and bone, while [18F]-FDG showed higher sensitivity for lymph node metastases.

Jian-Er Tan, Jiahao Xie, Ying Tian, Yuhang Ye, Yinjin Zou, Lilan Fu, Ye Dong, Penghui Sun, Yanjiang Han, Qiaoyu Wang, Li (…)2026-06-28
📄 medicine

Patient-Facing AI Chatbots vs Primary Care Physicians: A Standardized Patient Field Experiment in China

In a standardized patient field experiment across 62 Chinese primary care institutions, AI chatbots outperformed physicians in diagnostic accuracy and patient-centered communication but significantly increased the risk of low-value care by recommending excessive tests and inappropriate medications.

Yafei Si, Shaoqing Gong, Michael Thielscher, Hazel Bateman, Bingqin Li, Shanquan Chen, Duolao Wang, Ruopeng An, Yurun Me (…)2026-06-28
📄 medicine

Limited discriminative utility of resting-state heart rate variability for chronic pain–depression–anxiety comorbidity subtypes: an exploratory SHAP-based machine-learning analysis

This exploratory study utilizing SHAP-based machine learning found that resting-state heart rate variability has limited and unstable discriminative utility for distinguishing chronic pain–depression–anxiety comorbidity subtypes, particularly pain-depression and pain-anxiety dominant presentations, suggesting it is insufficient as a standalone biomarker for such classification.

Tian Xie, Jinchao Hu, Xin Tian, Guangyuan Ma, Jingchi Li, Jiexiang Yang, Yi Chen, Cheng Luo2026-06-28
📄 medicine

A Modified Lateral Skin Incision Reduces Wound Complications and hospital stay in Obese patients undergoing Total Knee Arthroplasty: A Propensity-Matched Cohort

This propensity-matched cohort study demonstrates that in morbidly obese patients undergoing total knee arthroplasty, a modified curved lateral skin incision significantly reduces wound complications, shortens hospital stays, and decreases anterior knee hypesthesia compared to the standard midline approach, while maintaining equivalent long-term functional outcomes.

Ahmed Saeed Younis, Sherif Mostafa Abdeldayem, Ibrahim Mahmoud Abdelmonem2026-06-28
📄 medicine

Clinical study on guidance of the timing of adaptive replanning for cervical cancer based on ADC values combined with tumor volume regression

This study demonstrates that early increases in apparent diffusion coefficient (ΔADC) during concurrent chemoradiotherapy for cervical cancer are strongly associated with tumor volume regression and can help identify patients for adaptive replanning, although replanning at the 15th fraction did not consistently offer dosimetric advantages over the 20th fraction.

YU QIAN MA, JIAXU yan, WENFEI li, DEFENG liu, LIYAN cao, YU MAO, LIJIE LIU, TAO GU2026-06-28