📄 Category

medicine

13473 papers

📄 medicine

Incremental Prognostic Value of Exertional Chest Pain Beyond PREVENT-Based Cardiovascular Risk Stratification: A Nationwide Prospective Cohort Study of Middle-Aged and Older Chinese Adults (CHARLS 2011–2020)

This nationwide prospective cohort study of Chinese adults demonstrates that simple, zero-cost questions about exertional chest pain significantly improve cardiovascular risk prediction beyond the PREVENT algorithm, particularly in females, thereby addressing a key evidence gap in the 2026 AHA/ACC/ADA/ASN guidelines.

Zhenghui Wang, Tianfeng Zhang, Yiming Wang, Long Zhao, Dongli Shen, Biao Kong, Yongwei Yao, Chenghua Wang, Junfang Guo (…)2026-10-20
📄 medicine

A browser-based neuro-ophthalmic examination simulator for medical students: rule-based scenario generation and internal review

This paper describes the development and internal review of a Persian-language, browser-based neuro-ophthalmic examination simulator for medical students, while noting that its educational effectiveness and assessment validity remain unproven due to the lack of independent clinical evaluation and prospective learner studies.

Amir Rahmanian sharifabad, Samira Jalalifar, Kimia Ashoorzadeh2026-10-20
📄 medicine

Bridging the Gap Between Infection Prevention Guidance and Dementia Care: A Qualitative Study of HealthcareProfessionals’ and Family Caregivers’ Experiences

This qualitative study of UK healthcare professionals and family caregivers reveals that generic infection prevention guidance often fails to accommodate the specific needs of people with dementia, highlighting the urgent need for co-designed, accessible, and person-centred communication strategies to bridge the gap between safety protocols and practical dementia care.

Bethany Linder, Jackie A. Cassell, Eddy J. Davelaar, Dorina Cadar2026-10-20
📄 medicine

Determinants of Complementary Food Handling Practices in Conflict-Affected Tigray, Ethiopia: A Qualitative Exploration

This qualitative study reveals that while mothers in conflict-affected Tigray possess knowledge of safe complementary food handling, their ability to practice it is systematically undermined by severe structural constraints, including WASH insecurity, poverty, and fragmented health services, necessitating a shift from individual behavior-change education to structural interventions that restore essential resources and environments.

kahsay amare, Gebretsadik Berhe, Girmatsion Fisseha, Shifare Berhe2026-10-20
📄 medicine

Seated Sensorimotor Exercise for Functional Mobility in Older Adults With and Without Diagnosed Dementia: A Six-Month Non-Randomised Controlled Study

This six-month non-randomised controlled study involving 90 older adults found that a supervised seated sensorimotor exercise programme significantly reduced primitive reflex burden and improved functional mobility, although the certainty of the mobility improvement varied by analysis method and the findings do not yet establish causality or fall reduction.

Erzsébet Stephens-Sarlós, Attila Szabo, Fanni Küplen, Patrick Stephens, Angéla Somogyi, Edmond Girasek2026-10-20
📄 medicine

Iron Therapy for Heavy Menstrual Bleeding Related Iron Deficiency Anaemia: Efficacy, Tolerability and Evidence Gaps for Women with Diabetes Mellitus. A Systematic Review

This systematic review concludes that while intravenous iron offers faster haematological correction than oral iron and shows broadly similar efficacy among different intravenous formulations for heavy menstrual bleeding-related anaemia, there is a critical lack of evidence regarding treatment efficacy, tolerability, and impact on glycated haemoglobin specifically for women with diabetes mellitus.

Grace Komuhangi2026-10-20
📄 medicine

Measurement definition, reference availability and testability shaped the verdicts on classical ECG rules in routine hospital data

This retrospective analysis of MIMIC-IV-ECG data evaluated thirteen claims regarding ten classical ECG rules, finding that while none were refuted, their diagnostic utility and verdicts were heavily shaped by measurement definitions, reference availability, and testability, with voltage criteria and Q-waves showing limited diagnostic information and QTc >500 ms confirming a mortality association but identifying only a small fraction of at-risk patients.

Leo Probst2026-10-20
📄 medicine

Interacting Role of Social Determinants of Health and Hearing Loss on Cognitive Decline: An ACTIVE Longitudinal Study

This longitudinal study using ACTIVE data reveals that while hearing loss predicts cognitive decline, the severity of memory and reasoning deterioration is significantly mitigated by favorable social determinants of health, such as high healthcare access and neighborhood resources, particularly for individuals with uncorrected hearing loss.

Nathalie Gider, Cynthia Felix, Megan C. Fitzhugh, Caitlin A. Northcutt, Michael, Karlene Ball, George Rebok, Tyler Bell2026-10-20
📄 medicine

Salivary 1,5-Anhydroglucitol in Type 2 Diabetes: Evidence, Assay Barriers, and Point-of-Care Readiness

This review concludes that while salivary 1,5-anhydroglucitol shows promise as a noninvasive adjunctive marker for detecting recent glycemic dysregulation in Type 2 diabetes, current evidence is insufficient for routine clinical adoption due to methodological limitations and the lack of validated point-of-care devices.

Andrea Basualdo Allende, Sarah Sadat Ehsani, Pascal Eber, Mohadeseh Alimohammadi, Alexander Ariel Padron Gonzalez, Rudi (…)2026-10-20