📄 medicine

Survival and Complication Patterns Following Transhiatal Esophagectomy in Patients with Locally Advanced Esophagogastric Junction Adenocarcinoma

This retrospective study of 101 patients with locally advanced esophagogastric junction adenocarcinoma undergoing transhiatal esophagectomy demonstrates that while the procedure yields acceptable oncologic outcomes, it is associated with substantial postoperative morbidity and mortality, with pathological stage, nutritional status, smoking history, and comorbidities identified as key predictors of survival and complications.

Amirmasoud Karimi, Mojtaba Ahmadinezhad, Seyed Alireza Hosseini, Shima Ahmadikia, Amirhossein Hajialigol, Sanaz Mohammad (…)2026-06-28
📄 medicine

Intraoperative intravenous methadone dose and postoperative pain outcomes in CABG patients: a retrospective cohort study

This retrospective cohort study of 41 CABG patients found no statistically significant differences in postoperative opioid consumption, pain scores, ICU length of stay, time to extubation, or QTc prolongation between those who received low-dose (<20 mg) versus high-dose (≥20 mg) intraoperative intravenous methadone.

Marissa Angelich, Wan-Ting Huang, Ashley Ta2026-06-28
📄 medicine

Heterogeneity in quality of life among patients receiving first postoperative chemotherapy for gastric cancer: A latent profile analysis of psychosocial and symptom pathways

This study identifies three distinct latent profiles of health-related quality of life among gastric cancer patients undergoing first postoperative chemotherapy and reveals that social support influences quality of life through a significant chained pathway involving resilience, fear of progression, and symptom experience, thereby supporting the need for personalized, integrated supportive care.

Nan Wang, Jie Zhang, Chaonan Fei, Ye Ding, Liping Yang, Peibei Duan2026-06-28
📄 medicine

Perspectives of healthcare providers on differentiated service delivery of long-acting cabotegravir and rilpivirine in clinics and community settings in England: findings from the ILANA non-randomised implementation study

The ILANA study demonstrates that healthcare providers in England find the differentiated service delivery of long-acting injectable CAB + RPV in both clinic and community settings to be largely feasible, acceptable, and appropriate, provided that implementation prioritizes patient needs, equitable access, and provider ownership of the process.

Rosalie Hayes, Sara Paparini, Yuk Lam Wong, Joanne Haviland, Kyle Ring, Vanessa Apea, Bakita Kasadha, Tristan J. Barber (…)2026-06-28
📄 medicine

Initial outpatient clinical characteristics associated with subsequent conversion from mild cognitive impairment to dementia: a retrospective exploratory study

This retrospective study identifies that older age, fewer subjective memory complaints, lower independence in instrumental activities of daily living, and specific cognitive deficits at the initial outpatient visit are key clinical characteristics associated with the subsequent conversion of mild cognitive impairment to dementia.

Natsuko Arimatsu, Marin Okada, Aya Matsumura, Shigeki Hirano, Ayumi Amemiya2026-06-28
📄 medicine

Robotic-Assisted Compartmental Dissection for Retroperitoneal Sarcoma: A Feasibility Study on Cadavers with the Da Vinci Xi System

This cadaveric feasibility study demonstrates that robotic-assisted multivisceral compartmental resection for retroperitoneal sarcoma using the da Vinci Xi system is technically achievable with standardized, side-specific port templates, supporting cautious future evaluation in carefully selected patients.

Jonas Wakker, Adrian Sagebiel, Victoria van Rüth, Simone Schewe, Nathaniel Melling, Felix Nickel, Oliver Mann, Thilo Hac (…)2026-06-28
📄 medicine

Indigenous Australians’ Lived Experiences of Diet, Nutrition, and Oral Health: A Qualitative Study

This qualitative study of 136 Indigenous Australian adults reveals that dietary choices and oral health outcomes are shaped by a complex interplay of individual awareness, structural barriers, and the enduring impacts of colonization, highlighting the critical need for community-led, culturally safe strategies that prioritize self-determination and food sovereignty to achieve oral health equity.

Sonia Nath, Johanna Groundwater, Ria Aiyar, Nicolas Reid, Gina L. Guzzo, Kostas Kapellas, Lisa Jamieson2026-06-28
📄 medicine

inproTeamED - Interprofessional clinical assessment in the emergency department: A qualitative analysis

This qualitative study of 13 emergency department staff interviews reveals that while nurses and physicians share core assessment factors and generally value flat-hierarchy collaboration, their clinical reasoning differs in emphasis on physical examination and cognitive reflection, with successful interprofessional teamwork further dependent on addressing structural challenges like digitization usability.

Rena Isabel Prof. Dr. med. Amelung2026-06-28
📄 medicine

Curve type-specific sequential rod insertion strategy in combined anterior–posterior surgery for biplanar correction of degenerative lumbar kyphoscoliosis

This study demonstrates that a curve type-specific sequential rod insertion strategy in combined anterior–posterior surgery is a feasible approach for achieving simultaneous biplanar correction in degenerative lumbar kyphoscoliosis, although preoperative type C curves, fewer anterior fusion levels, and greater coronal imbalance are associated with residual malalignment.

Jin-Sung Park, Se-Jun Park, Dong-Ho Kang, Chong-Suh Lee, Hyun-Jun Kim2026-06-28
📄 medicine

Diagnostic accuracy of capnography in verification of nasogastric tube placement: A prospective multicentre study

This prospective multicentre study demonstrates that capnography is a highly accurate and cost-effective first-line tool for excluding inadvertent airway placement of nasogastric tubes, showing superior performance compared to radiography alone while significantly reducing healthcare costs.

Janita Pak Chun Chau, Danny Wah Kun Tong, Suzanne Hoi Shan Lo, Savina Yee Man Sze, Peter Chi Keung Lai, Josephine Yuen M (…)2026-06-28