📄 medicine

Effect of embryo transfer catheter incubation strategy on pregnancy and live birth outcomes: a retrospective comparative cohort study

This retrospective cohort study demonstrates that incubating the embryo-carrying inner catheter, either alone or combined with the outer sheath, significantly improves clinical pregnancy and live birth rates compared to incubating only the outer sheath during embryo transfer.

Chandan V. Salunke, Shravani K. S. Parker, Ameet A. Naik, Abhijit J. Kamat2026-06-26
📄 medicine

Dual-Targeting of Tumor Cells and Neovasculature for Synergistic Photoimmunotherapy: A CD105 Nanobody-Driven Nanoplatform Reprograms the Immune Microenvironment

This study presents a CD105 nanobody-functionalized layered double hydroxide nanoplatform that delivers indocyanine green for synergistic photodynamic/photothermal therapy, effectively reprogramming the tumor immune microenvironment by inducing immunogenic cell death and robust T-cell responses to suppress tumor growth and angiogenesis.

Xuandong Lin, Sandar Moe Moe Sint, Qing Huang, Shuai Li, Xueling Ma, Liji Mo, Hao Zhang, Jindong Long, Xintong Xie, Fang (…)2026-06-26
📄 medicine

Self-Care Adherence and Associated Determinants among Adults with Type 2 Diabetes Mellitus in Ethiopia: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis of 18 studies reveals that only 50.46% of adults with type 2 diabetes in Ethiopia adhere to recommended self-care practices, with medication adherence being the highest and self-monitoring the lowest, while highlighting that access to glucometers, diabetes education, social support, and association membership significantly improve adherence, whereas rural residence is a barrier.

Getachew Tilaye Mihiret, Mikiyas Muche Teshale, Menberu Gete, Kumlachew Solomon Wondmu, Addisu Getie, Melaku Laikemariam (…)2026-06-26
📄 medicine

Fragmented Data, Fragmented Decisions: Integrating Knowledge Systems in Modern Pharmacotherapy

This paper argues that the pharmaceutical ecosystem's reliance on fragmented data undermines decision-making and limits the efficacy of AI, necessitating a paradigm shift toward integrated, interoperable knowledge systems that transform isolated information into actionable, equitable clinical insights.

Alhasan Alsahti Ahmed, Xintong Fan, Al Imran, Changbiao Li, yanpeng Zhang, Qingyu Wang2026-06-26
📄 medicine

Burden and determinants of anemia among pregnant women in Africa: An umbrella review

This umbrella review of 10 systematic reviews involving over 229,000 pregnant women in Africa reveals a pooled anemia prevalence of 37.68% driven primarily by low dietary diversity, inadequate micronutrient supplementation, and infections, underscoring the need for targeted, multi-faceted interventions to improve maternal health outcomes.

Alemken Eyayu Abuhay, Tadele Amare Zeleke, Demiss Mulatu Geberu, Serku Abate Mihret, Mesafint Yihalem Belie, Kassa Kefal (…)2026-06-26✓ Author reviewed
📄 medicine

Assessment of Different Removal Techniques for Bioceramic-based Root Filling Material in Long Oval Canals of Mandibular Premolars: A Micro-Computed Tomographic Study

This micro-CT study of mandibular premolars with long oval canals found that no single retreatment technique using ProTaper Universal, solvents, or specific tips was superior in removing bioceramic-based iRoot SP sealer and gutta-perpa, with the apical third retaining the most residual material regardless of the method used.

W.A Alawneh, Z.A Che Ab Aziz, HMA Ahmed, SM Munusamy, N Ibrahim2026-06-26
📄 medicine

Essential components of successful disease prevention and control measures implemented in border areas: A qualitative analysis involving multiple countries in the Mekong region

This qualitative study of 44 health workers across four Mekong border countries identifies three essential components for successful disease prevention and control in the region: robust policies and information systems, skilled and supported health workers, and adequate infrastructure and standard tools.

Thapakorn Ruanjai, Anusorn Udplong, Thanatchaporn Mulikaburt, Ratipark Tamornpark, Chalitar Chomchei, Jirarat Surinta, P (…)2026-06-26
📄 medicine

A Critical Incident Study of Fall Events in Older Adults from a Fall Prevention Program in Kerala, India

This qualitative study of older adults in Kerala, India, reveals that fall and near-fall events are multifactorial incidents shaped by environmental hazards, health conditions, and gendered daily roles, necessitating integrated, culturally responsive prevention strategies that address environmental modifications, chronic disease management, and behavioral adaptations.

Devika Rajeesh, Kavya S, P M Gopika, B Aravind Chandru, Thusharamol N S, Rekha M Ravidran2026-06-26