653 papers
Microbiology explores the invisible world of tiny life forms that shape our health, environment, and even the air we breathe. From bacteria and viruses to fungi and parasites, this field investigates how these microscopic organisms interact with us and each other, driving everything from disease outbreaks to beneficial fermentation processes. Understanding them is crucial for developing new medicines, improving food safety, and combating global health challenges.
At Gist.Science, we make the latest discoveries in this dynamic field accessible to everyone. We process every new preprint uploaded to bioRxiv in this category, transforming dense academic findings into both clear, plain-language explanations and detailed technical summaries. This ensures that whether you are a student, a researcher, or simply curious, you can grasp the significance of cutting-edge science without getting lost in jargon.
Below are the most recent papers in microbiology, curated and summarized directly from the bioRxiv server to keep you at the forefront of discovery.
This study demonstrates that while bacterial phylogeny predicts virulence in Staphylococcaceae infections, it does not predict phage efficacy in vivo, revealing a lack of correlation between in vitro and in vivo outcomes and highlighting the critical role of environmental factors in therapeutic phage selection.
This study evaluates and recommends a specific probe-based qPCR system for routine clubroot diagnostics in Canada, demonstrating its superior sensitivity to detect *Plasmodiophora brassicae* at levels as low as 1,000 spores per gram of soil, which is below the threshold for visible disease symptoms.
This study introduces a novel ex vivo gut mucosal explant assay that quantifies both viral replication and transfer to demonstrate that methamphetamine exposure significantly increases gut tissue susceptibility to HIV infection.
This study reveals that in *Stenotrophomonas maltophilia*, DSF-mediated quorum sensing integrates c-di-GMP signaling, the σ54 transcriptional pathway, and metabolic reprogramming to orchestrate the switch between biofilm and motile lifestyles while modulating antibiotic resistance.
This study reveals that HIV-induced lymphoid tissue fibrosis occurs during the earliest stages of acute infection and is driven by macrophage-derived TGF-β, suggesting that immediate antiretroviral therapy may be insufficient to prevent or reverse this structural damage.
This study reveals that Ktedonobacteria, a widespread soil-dwelling bacterial class, possess highly diverse biosynthetic gene clusters primarily housed on recurrent chromid-like secondary replicons, significantly expanding our understanding of soil microbial chemical diversity and genome architecture.
This study demonstrates that West Nile virus lineage 2 exhibits higher transmission efficiency and requires lower infectious doses than lineage 1 across three mosquito species, with *Culex torrentium* identified as a highly competent vector despite its limited prior research.
This study demonstrates that untargeted metabolomics of human induced pluripotent stem cells can distinguish between Dengue and Zika virus infections by identifying virus-specific metabolic signatures and reveals that modulating tryptophan metabolism regulates viral replication, offering a promising complementary diagnostic and therapeutic strategy.
This study reveals that prevalent human gut phages encode modular Ig-like adhesins that mediate specific binding to and non-degradative trafficking of epithelial cells, highlighting widespread phage-human interactions with significant implications for phage therapy.
This study demonstrates that substituting lysine residues at positions 13 and 17 in histatin 5, particularly with arginine at K13 and tryptophan at K17, significantly enhances the peptide's proteolytic stability against *Candida albicans* proteases and salivary enzymes while improving its antifungal activity and biofilm inhibition capabilities.