1322 papers
Neuroscience explores the intricate machinery of the brain and nervous system, seeking to understand how we think, feel, and move. From the microscopic dance of individual neurons to the complex networks that shape our memories and behaviors, this field peels back the layers of our biological selves to reveal the origins of consciousness and disease.
At Gist.Science, we bring these discoveries directly from bioRxiv, the leading preprint server for biological sciences, to a broader audience. We process every new neuroscience preprint as it is uploaded, transforming dense academic manuscripts into clear, plain-language explanations alongside detailed technical summaries. This ensures that both curious readers and specialists can stay current with the latest breakthroughs before they are formally published.
Below are the latest neuroscience papers we have processed from bioRxiv, offering fresh insights into the workings of the mind.
This manuscript, which originally investigated behavioral unresponsiveness and impaired auditory event-related potentials in the anterior insula during rat absence seizures, has been withdrawn from bioRxiv because the corresponding author could not access the original data required to finalize the study.
This paper introduces a publicly available, population-scale canonical Hidden Markov Model trained on 1849 MEG recordings to provide a common reference framework for analyzing diverse M/EEG datasets in both sensor and source spaces, thereby eliminating the need for computationally expensive, study-specific model training.
This paper introduces two novel behavioral tasks, the "shooting aliens" and "hands-attack" paradigms, which overcome limitations in existing habit research by demonstrating that intra-block reversals and ecologically valid avoidance scenarios effectively capture robust, outcome-insensitive habitual behavior in humans suitable for clinical application.
This study presents the first ribosome-profiling analysis of the mouse suprachiasmatic nucleus, revealing that while canonical clock genes are primarily transcriptionally regulated, light stimulation induces significant translational upregulation of GAD1 to increase Gad67 protein levels, thereby establishing translational control as a distinct and critical layer in shaping circadian and light-responsive gene expression.
This study of 100 first-episode schizophrenia patients reveals that early-stage brain connectivity is characterized by a balanced mix of localized hyper- and hypoconnectivity rather than a global shift, while highlighting that data preprocessing choices critically influence whether hypoconnectivity appears dominant.
This study demonstrates that the mere generation of microsaccades is sufficient to directly modulate extrafoveal visual sensitivity through classic pre- and post-saccadic processing changes, establishing these subliminal eye movements as an integral causal component of attention rather than just a reflection of it.
This fMRI study provides empirical evidence that graded belief uncertainty engages specific brain regions, including the dorsomedial and dorsolateral prefrontal cortices, thereby validating the link between graded belief and doubt while conceptually replicating prior findings and aligning with classical philosophical theories of belief.
This study demonstrates that, contrary to predictions based on value-based decisions, a perceptual decoy effect does not reliably bias human choice in a rhesus-macaque paradigm, suggesting that context effects in perceptual tasks operate under narrower boundary conditions.
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This study demonstrates that in A53T transgenic mice modeling Parkinson's disease, astrocytes in the substantia nigra pars compacta exhibit a reactive phenotype with significantly increased numbers and accumulation of α-synuclein aggregates compared to wild-type controls, suggesting that early deficits in astrocytic clearance of these aggregates contribute to the region's vulnerability.