🧠 Category

neuroscience

1306 papers

Neuroscience explores the intricate machinery of the brain and nervous system, seeking to understand how we think, feel, and move. From the microscopic dance of individual neurons to the complex networks that shape our memories and behaviors, this field peels back the layers of our biological selves to reveal the origins of consciousness and disease.

At Gist.Science, we bring these discoveries directly from bioRxiv, the leading preprint server for biological sciences, to a broader audience. We process every new neuroscience preprint as it is uploaded, transforming dense academic manuscripts into clear, plain-language explanations alongside detailed technical summaries. This ensures that both curious readers and specialists can stay current with the latest breakthroughs before they are formally published.

Below are the latest neuroscience papers we have processed from bioRxiv, offering fresh insights into the workings of the mind.

🧠 neuroscience

In vivo motor unit decoding and in vitro cellular characterisation of spinal circuits for urination in adult mice

This study integrates in vivo motor unit decoding with in vitro cellular characterization to reveal the hierarchical recruitment patterns, distinct biophysical properties, and local circuit architecture governing perineal motor control during urination in adult mice, while demonstrating the inhibitory mechanism of tibial nerve stimulation on the external urethral sphincter.

Ozyurt, M. G., Nascimento, F., Pascual-Valdunciel, A., Dhillon, K., Bansal, V., Brownstone, R. M., Beato, M.2026-03-17
🧠 neuroscience

Beyond Neural Noise: Critical Dynamics Predict Slower Reaction Times in Adults With and Without ADHD

This study challenges the traditional view of neural variability as random noise by demonstrating that slower reaction times in both adults with and without ADHD are preceded by a shift toward critical dynamics, suggesting that increased variability reflects structured, meaningful neural processes rather than signal degradation, while also highlighting the limitations of between-subject correlations in inferring such mechanisms.

DallaVecchia, A., Zink, N., O'Connell, S. R., Betts, S. S., Noah, S., Hillberg, A., Oliva, M. T., Reid, R. C., Cohen, M. (…)2026-03-17
🧠 neuroscience

Impaired motor activity in a CRISPR SCA5 L253P knock-in mouse is associated with selective beta-III-spectrin subcellular redistribution in the cerebellum

This study characterizes a CRISPR-generated SCA5 L253P knock-in mouse model that exhibits impaired motor activity and selective cerebellar redistribution of beta-III-spectrin, leading to disrupted synaptic signaling and providing a platform for future therapeutic development.

Avery, A. W., O'Callaghan, B. L., Thiel, M. T., Denha, S. A., O'Callaghan, D. G., Cismas, E. M., Lamp, J., Orr, H. T., H (…)2026-03-17
🧠 neuroscience

Heightened Distraction under Competition in Obsessive-Compulsive Disorder

This study demonstrates that individuals with obsessive-compulsive disorder exhibit heightened visuocortical distraction and reduced attentional engagement when processing affective and disorder-relevant cues compared to controls, as evidenced by steady-state visual evoked potentials and the distraction under competition model.

McCain, K. J., Ayomen, E., Mirifar, A., Simpson Martin, H., Demeterfi, D., McNeil, D. J., DePamphilis, G., Hatem, R., Ne (…)2026-03-17
🧠 neuroscience

Sleep renormalizes learning-perturbed cortical population dynamics to stabilize memory

This study demonstrates that sleep stabilizes newly formed memories by renormalizing learning-perturbed cortical population dynamics, specifically by restoring flatter aperiodic EEG slopes induced by declarative learning back to steeper slopes during NREM sleep, a process that serves as a systems-level mechanism linking homeostatic plasticity to memory consolidation.

Ng, T., Barnes, M., Abedeen, A., Collignon, L., Patel, H., Vovcsko, N., Spencer, R. M. C.2026-03-17
🧠 neuroscience

Convergent cortical temporal axis: common cortical oscillatory modes

Using a fully data-driven analysis of resting-state MEG, this study reveals that large-scale brain dynamics are organized not along a single continuous hierarchical axis but by a finite set of reproducible spectral coordination modes that link microscale cellular and genetic properties to macroscale network organization, aging, and neurological disease.

Liu, X., Wang, S., Wu, X., Long, S., He, L., Liu, L., Cui, R., Yang, G.2026-03-17