Comparative genomic analysis reveals shared and distinct mechanisms of nasal polyps and chronic rhinosinusitis

This multi-population genome-wide association meta-analysis identifies shared and distinct genetic architectures between chronic rhinosinusitis and nasal polyps, revealing substantial shared liability while highlighting that immune-driven mechanisms play a more dominant role in nasal polyp heritability than epithelial factors.

Yuan, S., McVey, J. C., Hartmann, K. + 10 more2026-04-08📄 otolaryngology

Improving Automated Diagnosis of Middle and Inner Ear Pathologies by Estimating Middle Ear Input Impedance from Wideband Tympanometry

This study demonstrates that estimating middle ear input impedance from wideband tympanometry data, when combined with standard audiometric air-bone gaps, significantly improves the automated classification accuracy of stapes fixation and superior canal dehiscence compared to using air-bone gaps or absorbance metrics alone.

Kamau, A. F., Merchant, G. R., Nakajima, H. H. + 1 more2026-03-31📄 otolaryngology

A meta-analysis of bone conduction 80 Hz auditory steady state response thresholds in adults and infants

This meta-analysis of 27 studies concludes that while bone conduction auditory steady-state responses (BC ASSRs) are a reliable method for estimating hearing thresholds in adults and infants, significant variations based on age and frequency necessitate the development of specific correction factors to accurately predict behavioral thresholds.

Perugia, E., Georga, C.2026-02-23📄 otolaryngology