🧬 biology

Whole-genome resequencing reveals population genomic diversity and enables SNP fingerprinting for germplasm management in Saudi Arabian pearl millet (Pennisetum glaucum)

This study utilizes whole-genome resequencing of 49 Saudi Arabian pearl millet accessions to characterize their population structure and genetic diversity, ultimately developing a highly discriminating 150-SNP fingerprinting panel integrated with QR-code technology for effective digital germplasm management.

Naser B Almarri, Salwa M Mostafa, Sara Osman, Sara M Alomran, Mohanad A Ibrahim, Ibrahim Alrashidi, Omar A Al-Haidar, Ib (…)2026-09-17
🧬 biology

Whole-Transcriptome Profiling Reveals RNA Expression Dynamics and ceRNA Network Remodeling across Health, Sepsis, and Sepsis-Associated Acute Respiratory Distress Syndrome

This study utilizes whole-transcriptome sequencing of peripheral blood to characterize progressive dysregulation of mRNAs, lncRNAs, circRNAs, and miRNAs across health, sepsis, and sepsis-associated ARDS, revealing a remodeled ceRNA network that drives immune-inflammatory activation, extracellular matrix remodeling, and barrier dysfunction.

Qicheng Long, Yongkang Ye, Aifang Huang, Shuqing Liang, Wei Wang2026-09-17
🧬 biology

Performance of Polygenic Risk Scores for Breast Cancer in African Populations: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis reveals that while polygenic risk scores for breast cancer show modest predictive performance in African populations, European-derived models currently outperform those developed specifically for African ancestry, underscoring the critical need for greater genomic representation and recalibration to improve clinical utility.

RISSAME Djeneba Yasmina, Abibou SIMPORE, ZOURE Abdou Azaque, Barro Marcus, Moussa OUATTARA, Aida Djé Traoré, SAWADOGO Mo (…)2026-09-17
🧬 biology

Convergence of Artificial Intelligence and Cognitive Neuroscience Innovations and Future Directions

This review of 100 studies examines the interdisciplinary convergence of Artificial Intelligence and Cognitive Neuroscience, highlighting memory and attention as dominant research domains while addressing key technological applications, emerging directions like explainable AI, and critical ethical challenges to advocate for sustained collaboration in developing biologically grounded and socially responsible intelligent systems.

Uwem Johnson Ukpong, Otutu Margret Chetachi2026-09-17
🧬 biology

Impact of Cognitive Dual-Task Levels on Instrumented Timed Up and Go Performance: A Statistical and Machine Learning Analysis

This study demonstrates that increasing cognitive dual-task complexity significantly alters phase-specific gait performance and stability in healthy middle-aged adults, particularly during the walking-back phase, highlighting the value of instrumented Timed Up and Go analysis for detecting early cognitive-motor interference.

Abishek Shrestha, Zongyi Jiang, Farhan Ahnaf Rashid, Nathan D'Cunha, Raul Fernandez Rojas, Maryam Ghahramani2026-09-17
🧬 biology

Breeding period and nest survival of two endemic passerines on Fernando de Noronha Archipelago, Brazil

This study reveals that the endemic Noronha Vireo exhibits unusually high nest survival compared to the more vulnerable Noronha Elaenia, whose lower success rates highlight the urgent need for conservation measures such as invasive predator removal and habitat restoration on Fernando de Noronha.

Geisiane Sobral, Gabriela Arnoso, Larissa Amaral, Cecília Licarião, Bruna Miacci, Rosana Andrade Camilo, Mauro Galetti2026-09-17
🧬 biology

Only a third of Fusarium oxysporum formae speciales are monophyletic: a per-label and per-deposit audit of 363 public genomes

By auditing 363 public *Fusarium oxysporum* genomes, this study reveals that only one-third of formae speciales are monophyletic and that the current classification system is plagued by significant phylogenetic conflicts, taxonomic redundancy, and mislabeled or non-target genomes, arguing that *forma specialis* should be treated as an operational pathological category requiring independent evidence rather than a phylogenetic one.

Beyza Akal, Yasin Kaymaz2026-09-17
🧬 biology

Quantifying the impact of experimental hut design on intervention evaluation outcomes and predicted reductions in vectorial capacity

This study demonstrates that experimental hut design significantly influences mosquito behavior and the predicted reduction in vectorial capacity for insecticide-treated nets, highlighting the critical need to account for structural variations in trial data when forecasting population-level transmission impacts.

Emma Louise Fairbanks, Alphonce Assenga, Olukayode G Odufuwa, Raphael N'Guessan, Jason Moore, Sarah J Moore2026-09-17
🧬 biology

The STAU1-CD44v8-10 axis regulates the initiation and progression of lung squamous cell carcinoma through PI3K/AKT signaling

This study demonstrates that the STAU1–CD44v8-10 axis drives the initiation and progression of lung squamous cell carcinoma by sustaining PI3K/AKT signaling, a process triggered by cigarette smoke exposure that promotes malignant traits and poor patient prognosis.

lingrui shang, Shisheng Jiang, Nannan Wang, Qianqian Liu, Yimei chen, Tongran Zhang, Yun-shen Chan, Wenzhao zhong, feng (…)2026-09-17
🧬 biology

From resilient adults to fragile early life stages: salinity tolerance across the life cycle of the green panchax, Aplocheilus blockii

This study reveals that while the green panchax (*Aplocheilus blockii*) exhibits remarkable salinity tolerance as an adult, particularly under gradual acclimation, its early life stages are significantly more vulnerable, suggesting that recruitment in this species is primarily constrained by the salinity sensitivity of embryos and larvae.

Grace George, S. Thiruvarasu, Binu Varghese2026-09-17