1390 papers
This study demonstrates that focal anodal stimulation of the ventromedial prefrontal cortex improves working memory performance under elevated arousal by modulating task-related functional connectivity between attention-regulatory and sensory-processing brain regions.
This study investigates the role of the posterior cerebellum in aesthetic experiences by using transcranial direct current stimulation (tDCS) to reveal that anodal stimulation modulates feelings of being moved by art in complex ways, specifically increasing emotional engagement for individuals with low art experience and low-to-medium empathy while decreasing it for those with high art experience.
This paper introduces "armosis," a quantitative framework measuring the progressive reduction in theoretically possible biological entities across organizational levels, and demonstrates its application using a provenance-aware knowledge graph of human mitochondrial genomes to reveal increasing constraints from codons to the complete electron transport chain.
This paper evaluates the efficacy of frozen ResNet50 features for colon histopathology, finding that while transfer learning yields near-perfect detection accuracy and biologically plausible clustering, it does not eliminate the critical need for stain normalization, external validation, and explainability to address potential data leakage and bias.
This study demonstrates that epigenetic age estimates in blood vary by decades depending on the specific cell population assayed, a variation large enough to dominate biological signals and confound cross-study comparisons, thereby establishing cell composition as a critical methodological variable that requires standardized reporting.
This study reveals that the Arg156 polymorphism in HLA-B*35 enables T-cell discrimination not through static binding affinity, but by organizing a structured water-mediated electrostatic network that suppresses peptide flexibility and lowers the entropic penalty required for T-cell receptor triggering.
This study analyzes the canola rhizosphere microbiome using 16S rRNA sequencing of 8,701 samples to characterize diversity and identify a core microbiome, ultimately developing a highly accurate Random Forest classifier based on ASV features to predict plant health status.
This study demonstrates that chronic inflammatory pain impairs delayed gratification in rats by reorganizing the functional ensembles of lateral orbitofrontal cortex neurons, rather than simply reducing their overall activity, thereby disrupting the population coding of time-reward associations.
This study identifies and validates S100A8, S100A9, and S100A12 as significantly upregulated immune-related risk genes in sepsis patients, demonstrating their predominant expression in macrophages and potential involvement in the PI3K-Akt signaling pathway through integrated RNA sequencing, bioinformatics, meta-analysis, and experimental verification.
This paper proposes a theoretical framework called "Quantitative Biotheology" that claims a specific numerical sequence (10-5-6-5), derived from valence-bond constants and quantum orbital analysis, represents a divine mathematical constant essential for the thermodynamic stability and structural integrity of DNA.