🧬 biology

Molecular characterization of Babesia ovis in an enzootic focus in eastern Bosnia and Herzegovina

This study reveals that while the 18S rRNA gene of *Babesia ovis* exhibits low genetic diversity within an enzootic focus in eastern Bosnia and Herzegovina, the presence of multiple rare haplotypes across different villages and seasons indicates that the parasite is not uniform and requires higher-resolution markers and repeated sampling to fully characterize its local genetic structure.

Oliver Stevanović, Goran Vasilić, Andrea Radalj, Ana Vasić, Naida Kapo, Drago Nedić, Ivona Subić, Dragan Kasagić, Dragan (…)2026-11-02
🧬 biology

Habitat type outweighs urban proximity in shaping cavity-nesting hymenopteran communities

This study demonstrates that local habitat characteristics, specifically the distinction between forest fragments and organic crops, are more significant than urban proximity in shaping the structure, composition, and interaction networks of cavity-nesting hymenopteran communities, primarily through species turnover and interaction rewiring rather than simple species loss.

Luana Vieira Carlin dos Santos, Jean Pablo Alves de Deus, Jucélia Iantas, Maria Luisa Tunes Buschini2026-11-02
🧬 biology

A Human iPSC-Based Lung Organoid with Stromal and Macrophage Components for Pulmonary Fibrosis Modelling and Pharmacological Response Assessment

This study establishes a reconstructable human multicellular lung organoid model (hiLOFM) incorporating stromal and macrophage components that effectively mimics the complex pathophysiology of pulmonary fibrosis and enables the assessment of pharmacological responses to both established antifibrotics and novel therapeutics.

Huan Zou, Ze-Xin Chen, Yu Zhu, Suo-Ri-Ya Meng, Dian-Qi Wu, Yi Gao2026-11-02
🧬 biology

Human emotional chemical cues collected in situations of disgust or sadness modulate horses’ behaviour and physiology in a multimodal context

This study demonstrates that horses can discriminate between human chemical cues of sadness and disgust, exhibiting distinct physiological and behavioral responses—such as calmness to sadness and heightened arousal to disgust—that align with the specific arousal levels of these emotions when presented alongside matching visual and auditory cues.

Claire Ricci-Bonot, Margot Dromnelle, Julie Lemarchand, Fabien Cornilleau, Juliette Cognié, Fabrice Reigner, Jessica Plo (…)2026-11-02
🧬 biology

Australian isolates of cell fusing agent virus and Culex flavivirus provide new tools to study insect-specific flaviviruses

This study reports the first isolation of Cell fusing agent virus and Culex flavivirus from Australian mosquitoes, the creation of their first infectious clones, and the development of novel monoclonal antibodies, collectively providing essential new tools to advance research on insect-specific flaviviruses and mosquito-borne disease control.

Alyssa J Peterson, Isabella E McMahon, Lillian D Hall, Ryan A Johnston, Mahali S Argent, James R Potter, Devina Paramith (…)2026-11-02
🧬 biology

Development of a giant panda calprotectin-detecting immunoassay for non-invasive intestinal health monitoring

This study developed a species-specific immunological framework using recombinant giant panda calprotectin subunits and generated monoclonal antibodies to establish a semi-quantitative sandwich ELISA system for non-invasive monitoring of intestinal inflammation in giant pandas, addressing a critical gap in wildlife health surveillance.

Jingjie Wei, Licai Ma, Yu Qin, Yifan Wen, Zichen Liu, Wanrong Song, Li Liu, Zhiyang Huang, Haojie Xu, Yipeng Jin2026-11-02
🧬 biology

MolSanity: A Reliability Audit for Feature Attributions on Molecular Graph Neural Networks

MolSanity introduces a comprehensive reliability audit framework for molecular graph neural network feature attributions, revealing that faithfulness to the model does not correlate with chemical correctness or ground-truth localization, particularly under scaffold shifts, thereby demonstrating that explanation reliability must be evaluated on a case-by-case basis rather than assumed from faithfulness metrics alone.

Karthik Iyer, Nasser Sabar2026-11-02
🧬 biology

A Calibration Framework for Bridging Household-Structured Microscopic and Macroscopic Epidemic Models

This paper proposes a novel calibration framework that bridges the computational efficiency of macroscopic epidemic models with the structural accuracy of microscopic models by introducing a calibrated parameter to account for household clustering, thereby significantly reducing computation time while maintaining high fidelity to individual-level dynamics.

Rex Ndubuisi Ali, Nagesh Subbanna, Saswati Sarkar2026-11-02