1504 papers
This study presents high-quality, chromosome-level genome assemblies for five Balkan Brassicaceae species adapted to ultramafic substrates, utilizing PacBio HiFi and Hi-C technologies to provide foundational resources for comparative genomics and evolutionary adaptation research in this understudied biodiversity hotspot.
This study identifies distinct DNA methylation alterations associated with metastatic progression in primary colorectal tumors that persist after accounting for immune and stromal cell heterogeneity, revealing specific epigenetic signatures linked to gene silencing and potential biomarkers for metastatic risk.
This study developed a biocompatible, PEI-functionalized MIL-100(Fe) nanocarrier that effectively condenses plasmid DNA and demonstrates enhanced transfection efficiency with reduced cytotoxicity in colon cancer cells, presenting a promising nonviral gene delivery system.
This study demonstrates that a continuous evolution system can rapidly reprogram bacteriophage T7 to infect *Yersinia pestis* by evolving its tail fiber protein, resulting in a potent therapeutic candidate that fully protects mice from pneumonic plague when combined with antibiotics.
This study employs a physics-based acoustic framework to demonstrate that higher proficiency in EFL speech correlates with measurable improvements in prosodic features—such as pitch range, vowel space area, and intensity contrast—which collectively serve as strong predictors of enhanced intelligibility.
This paper proposes a novel synchronization-driven synaptic learning rule for self-organizing probabilistic spiking neural networks, demonstrating that moderate feedback inhibition optimizes pattern separation and stability, thereby outperforming conventional Hebbian learning and enabling successful obstacle avoidance in a simulated autonomous agent.
This study on adolescent female water polo players demonstrates that combining 60% 1RM load with 40% velocity loss induces the most significant and persistent neuromuscular fatigue, while identifying CK, RPE, and RSImod as highly sensitive indicators for monitoring training responses across different load and velocity loss combinations.
This study demonstrates that applying integrative taxonomy to marine invertebrates from the Flemish Cap significantly expands and refines DNA reference databases, thereby enhancing the accuracy of biodiversity assessments and supporting non-invasive conservation strategies for Vulnerable Marine Ecosystems.
This study demonstrates that the transcription factor Dichaete (the *Drosophila* homolog of Sox2) is sufficient to reactivate latent organogenic potential in differentiated epithelia, inducing the *de novo* formation of entire wings and other appendages through a conserved mechanism that relies on local positional cues and a specific downstream mediator network.
By integrating behavioral experiments, neurocomputational modeling, and EEG recordings, this study provides convergent evidence that auditory–motor feedback control in speech production is organized at the syllable timescale, where feedback delays disrupt speech and modulate neural suppression specifically when aligned with syllable duration.