4 papers
Toxicology explores how chemicals and substances interact with living organisms, helping us understand everything from everyday household safety to the risks of environmental pollutants. This vital field investigates how toxins enter the body, what damage they cause, and how we can detect or treat exposure, bridging the gap between laboratory findings and real-world health outcomes.
On Gist.Science, we ensure these critical insights reach everyone by processing every new toxicology preprint from medRxiv. Our team transforms complex research into both plain-language overviews and detailed technical summaries, making cutting-edge discoveries accessible without sacrificing scientific rigor.
Below are the latest papers in toxicology, offering fresh perspectives on chemical safety and public health.
This study developed and validated a stratified predictive model using only routine admission biomarkers that significantly outperforms the current ALTxAPAP benchmark in identifying acetylcysteine-treated acetaminophen overdose patients at high risk of hepatotoxicity, thereby enabling more precise selection for intensified therapy.
This study evaluates the efficacy and safety of various mosquito repellents in South Asia, finding that while DEET-based creams offer the highest protection and natural formulations the lowest, mosquito coils provide the longest duration but pose the greatest health risks due to combustion emissions, highlighting a critical trade-off between effectiveness and safety that necessitates informed consumer choices and improved regulatory oversight.
This study demonstrates that the abnormal biochemical profiles observed in HIV-exposed uninfected infants are primarily driven by antiretroviral medication, specifically efavirenz, which disrupts key metabolic pathways including steroids, tryptophan, and bile acids.
This study demonstrates that a reproducible postmortem metabolomic fingerprint, identified via high-resolution mass spectrometry in a national cohort of 51 fatal insulin intoxications, can reliably distinguish insulin-induced deaths from other causes even after insulin degradation, offering a valuable complementary tool for forensic diagnosis.