Comparative Time–Space Evolution of Bundibugyo Ebolavirus Glycoprotein Across the 2007, 2012, and 2026 Outbreaks
This study presents a comprehensive comparative analysis of Bundibugyo ebolavirus glycoprotein evolution across the 2007, 2012, and 2026 outbreaks, identifying 21 core substitution sites concentrated in variable domains while confirming the strict conservation of critical functional regions to establish a standardized framework for future genomic surveillance.