📄 medicine

Evaluation of the effectiveness of Photobiomodulation Therapy in the management of Chemoradiotherapy Induced Oral Mucositis in Head and Neck Cancer Patients: A Prospective Non-Randomized Interventional Study

这项前瞻性非随机干预研究表明,光生物调节疗法在减轻化疗放疗诱导的口腔黏膜炎严重程度、缓解疼痛和灼热感以及改善头颈部癌症患者营养状况方面,比常规护理更有效。

Dhara Ponda, Raghunand Sindhe, Meghana Maruthi, Anirudh VS, Kirthi Koushik A S, Akshaya Murugan2026-07-13
📄 medicine

Diagnostic Accuracy of Point‑of‑Care Ultrasound versus Neck Radiography for Laryngotracheal Stenosis: Complementary Roles in a Resource‑Limited Triage Pathway

这项前瞻性研究表明,床旁超声与颈部放射成像在喉气管狭窄的诊断中具有互补的优势,其中超声在声门部位表现优异,而放射成像在胸廓入口处表现更佳,这提示一种结合解剖学引导的分诊路径,有望在无法使用 CT 的资源受限环境下改善气道评估。

Gerhard Johan Klopper, Lufunda Lukama, Oladele Vincent Adeniyi2026-07-13
📄 medicine

OPTIMISE-ing consent in clinical trials: recommendations for designing accessible consent processes to address communication and decision-making needs as a barrier to participation

OPTIMISE研究开发了一个包含三项指导原则和七个实践领域的综合框架,旨在帮助研究人员设计无障碍的临床试验知情同意流程,从而克服能力受损人群在沟通和决策方面的障碍。

Victoria Shepherd, Martina Svobodova, Mark Jayes, Anna Volkmer, Amy M Russell, Julia Wade, Maximilian Clark, Shaun Trewe (…)2026-07-13
📄 medicine

Cervical Er:YAG Laser in Low-Risk CIN Management: A Promising Option Compared to Expectant Management and Conservative Treatments — A Pilot Study

这项初步研究表明,在管理低风险宫颈发育异常方面,颈部 Er:YAG 激光治疗与二氧化硅基阴道凝胶相比,具有更优的阴道镜下病变退缩率和 HPV 转阴率,同时尽管在后者组中存在极小的进展风险,该疗法仍能提供比观察等待治疗更迅速的缓解。

Suleyman Engin Akhan, Egemen Koyuncu, İpek Evruke, İnci Sema Tas, Sibel Balci, Cenk Yasa2026-07-12
📄 medicine

Burden, Patterns, and associated factors of post-kidney transplant infections among renal transplant recipients in Ethiopia: a retrospective study

这项针对埃塞俄比亚203例肾移植受者的回顾性研究显示,移植后感染负担沉重,主要为细菌感染,且多发生于第一年内,其中居住在亚的斯亚贝巴被确定为一个显著的相关因素。

Hiwot Beyene Mengistu, Absalat Serawit Negussie, Azeb Kebede Woldetsadik, Ayantu Tesfaye Lemma, Addisu Melike Ejigu, Won (…)2026-07-12
📄 medicine

Economic evaluation of topical ketorolac and nepafenac prophylaxis for early-stage retinopathy of prematurity: a multicenter real-world study in Colombia

这项在哥伦比亚开展的多中心真实世界研究发现,虽然与仅进行监测相比,局部使用酮咯酸和奈帕芬酸预防早产儿视网膜病变与更低的成本相关,且在酮咯酸的情况下还具有更高的质量调整寿命年,但研究结果尚不足以支持其常规应用,并强调了开展高统计效能随机对照试验的必要性。

Marudys Stella Mestra Burgos, Giliana García-Acevedo, Jorge Eduardo Silva Moreno, Karol Valeria Guerrero Beltrán, Wilman (…)2026-07-12
📄 medicine

Electro-acupuncture combined with adjuvant chemotherapy in gastric cancer (EAGER-2): a protocol for a multicenter randomized controlled trial

EAGER-2研究是一项多中心、受试者盲法、安慰剂对照的随机试验,旨在验证电针结合辅助化疗在改善胃切除术后胃癌患者无病生存期及其他临床结局方面的有效性。

Yuxing Hu, Xuesong Chang, Xiaoshu Chai, Ziyan He, Jiaming Liu, Zexing Zhang, Tianlin Wang, Yadong Chen, Yihan He, Yanjua (…)2026-07-12
📄 medicine

Dietary and chemical factors concurrently related to overweight in children and young adults – A cross-sectional Exposome-Wide Association Study (ExWAS)

这项针对超过41,000名2至25岁美国受试者的横断面ExWAS研究识别出了91种与超重相关的饮食及化学暴露因素,并强调虽然大多数一致因素都与较低的几率相关(例如纤维、铜和叶酸),但很少有因素能一致地与较高的几率相关(显著包括γ-生育酚和可替丁)。

Anne Kristine Christensen, Cecilia Ramlau-Hansen, Thorkild Sorensen, Olivier Jolliet, Christina Dahm2026-07-12