📄 medicine

The Integrated Behavioral-Socioecological Framework (IBSF): Unifying Behavioral Mechanisms and Multi-Level Context for Health Behavior Research

整合行为-社会生态框架(IBSF)将五种互补的行为模型统一为一个矩阵,在个体、社会和环境层面内,围绕能力、机会和动机对决定因素进行组织,从而通过将概念重叠视为复杂系统的特征而非冗余,解决了健康行为研究中的碎片化问题。

Jennifer N. Wells, Yetunde Tagurum, Gigi A. Gonzales, Vickie Cater, Kimberly J. Kiplagat, Heidy Pickles, Sandra Baer, Ke (…)2026-09-08
📄 medicine

Composite Dietary Antioxidant Index and Reduced Risk of Inflammatory Bowel Disease: Evidence of Protective Association for Crohn's Disease Mediated by Biomarkers

这项研究表明,较高的复合膳食抗氧化指数(CDAI)与克罗恩病风险降低显著相关,但与溃疡性结肠炎无关,且这种保护作用部分是通过较低水平的谷氨酰转肽酶(GGT)和C反应蛋白(CRP)介导的。

Yongjia Li, Dan Wu, Xuemei Lian, Yi Tao, Qing Zhou, Yantong Zhou, Qiuping Luo, Hongjia Yan, Ting Peng, Yuanlian Ouyang (…)2026-09-08
📄 medicine

Correction of Neglected Clubfoot With Midfoot Closed Wedge Osteotomy and Circular External Frame

这项针对21例患者的回顾性研究表明,中足闭合楔形截骨术结合环形外固定是治疗遗漏性马蹄内翻足的一种有效方法,成功纠正了严重的多平面畸形并恢复了功能性平足,且并发症发生率在可接受范围内。

Maurizio A. Catagni, Daniele Pili, Maria Luiza Philippi, Mohamed Rohayem, Jacek Parylo, Wojciech Bocheński, João Vitor L (…)2026-09-08
📄 medicine

Long-term Outcomes of Radical Prostatectomy versus Radiation Therapy for High- and Very High-Risk Localized Prostate Cancer: An IPTW Analysis from a Multi-center Asian Database

这项利用逆概率治疗加权法的多中心亚洲研究表明,对于高危和极高危局限性前列腺癌患者,与放射治疗相比,根治性前列腺切除术在总生存期和癌症特异性生存率方面均具有显著优越的预后结果。

Chih-Wei Chu, Hui Ying Liu, Yin Lun Chang, Yi Yang Liu, Hung-Jen Wang, Yen-Ta Chen, Yuan-Tso Cheng, Chih-Hsiung Kang, We (…)2026-09-08
📄 medicine

Chemotherapy-induced immunogenic hub restores NK cell activity via P2X7R in NSCLC

这项研究表明,化疗通过上调激活配体并诱导细胞衰老,增强了非小细胞肺癌中自然杀伤(NK)细胞介导的抗肿瘤活性,而药理学抑制P2X7受体能进一步与化疗产生协同作用,从而提升NK细胞的浸润与细胞毒性,尤其是在缺乏可靶向分子改变的肿瘤中。

Martina Bedeschi, Elena Cavassi, Valérie Vouret-Craviari, Alessia Ciarrocchi, Benedetta Donati, Guylène Rignol, Véroniqu (…)2026-09-08
📄 medicine

Trajectories of postpartum depressive symptoms over the first two months and subthreshold early symptoms as predictors of late-onset elevation: a retrospective cohort study

这项回顾性队列研究表明,产后抑郁症状在第一个月达到高峰,且产后一周时的爱丁堡产后抑郁量表(EPDS)阈下评分(5-9分)能显著预测后期症状的上升,这提示常规筛查应在第一周之后进行延伸,以包括对高风险女性的重新评估。

Shu-Ying Chen, Shih-Peng Mao2026-09-08
📄 medicine

A Prolonged Course of Hepatosplenic Melioidosis with Persistent Abscesses in Transfusion-Dependent β-Thalassemia Before Hematopoietic Stem Cell Transplantation: A Case Report

本病例报告描述了通过联合抗菌治疗和分阶段腹腔镜清创术,成功管理了一例患有输血依赖性 β-地中海贫血并伴有难治性肝脾类鼻疽症的 17 岁患者,该方案最终使患者在未发生感染复发的情况下安全完成了造血干细胞移植。

Jiamin Zhang, Yehua Wu, Liheng Ma, Yuefu Zhan2026-09-08
📄 medicine

A comparison of indoor and outdoor malaria vectors in a longitudinal cohort study in Webuye, Western Kenya

一项在肯尼亚西部韦布耶开展的纵向研究发现,虽然大多数疟疾媒介和受感染蚊子是在室内采集到的,且孢子体率达4.8%,但室外媒介主要以动物为食,并无证据表明其会对疟疾传播做出贡献,尽管多样化的非传统物种的存在构成了潜在的隐蔽威胁。

Lucy Abel, Samuel Kahindi, Daniel Onguru, Shehu Awandu, Mark Amunga, Millicent Cherono, Linda Maraga, Dancan M. Wakoli (…)2026-09-08