234 papers
Bioengineering sits at the vibrant intersection of biology and engineering, where scientists design new tools to understand life and solve real-world problems. From creating artificial organs to developing smart materials that mimic natural tissues, this field turns complex biological questions into tangible innovations that improve human health and our environment.
At Gist.Science, we track every new preprint in this category directly from bioRxiv. Our team processes each submission to provide both plain-language explanations for curious minds and detailed technical summaries for researchers, ensuring these cutting-edge discoveries are accessible to everyone. Below are the latest papers in bioengineering that have recently appeared on bioRxiv.
This study establishes a comprehensive workflow integrating rheological characterization, computational fluid dynamics, and experimental validation to predict and assess the impact of shear stress on the viability and function of endothelial-epithelial co-cultures during extrusion bioprinting with GelMA hydrogels.
This study demonstrates that a simplified single-IMU visual biofeedback system using a Lower Limb Trajectory Error metric can effectively modify gait mechanics in able-bodied adults, inducing whole-limb reorganization across multiple segments rather than isolated joint changes, although the efficacy of adaptation depends on the specific movement target and feedback formulation.
This study utilizes subject-specific musculoskeletal modeling to demonstrate that trunk posture, movement direction, and magnitude significantly alter intervertebral loading and paraspinal muscle force asymmetry in adolescents with idiopathic scoliosis, with flexion and convex-sided movements generally producing the greatest biomechanical imbalances.
This study demonstrates that intrinsic extracellular matrix composition dictates tissue-specific susceptibility to decellularization damage, establishing a composition-driven strategy that shifts quality assessment from simple DNA removal toward preserving biologically relevant ECM components to enable the rational design of regenerative biomaterials with tissue-specific mechanical and biological properties.
This study demonstrates that the fluorescent marker Carbotrace 480, combined with Snailase treatment, provides an effective method for detecting protoplasts in a pigment-deficient *Chlorella sorokiniana* mutant, thereby facilitating the genetic optimization of this microalgae for sustainable nutrient production.
This study establishes optically transparent *Aiptasia* larvae as a validated model for coral bleaching and introduces SYMPHONY, a machine-learning image-analysis pipeline that enables rapid, high-throughput, and accurate phenotyping of symbiotic algae localization under heat stress.
The paper introduces CONAN-SWIFT, a rapidly deployable platform that integrates computational design, RT-LAMP amplification, and CRISPR-Cas3 detection to enable sensitive, portable diagnosis of emerging RNA viruses within approximately three weeks of sequence availability.
This paper introduces a transferable pipeline combining a light sheet microscope with machine learning-based processing to overcome speed, phototoxicity, and data complexity barriers, thereby enabling practical long-term and high-speed volumetric fluorescence lifetime imaging (vFLIM) in living systems.
This paper presents a low-cost (~$700), open-source monophasic transcranial magnetic stimulator that utilizes a thyristor-driven capacitor discharge and ZVS charging circuit to generate therapeutic-level electric fields while incorporating multiple safety features and a method for estimating cortical stimulation strength.
This study demonstrates that silicate-phosphate substituted hydroxyapatite co-doped with lithium, europium, and gadolinium ions serves as a multifunctional biomaterial platform that modulates early molecular pathways in human bone marrow stromal cells without significantly enhancing their terminal differentiation into osteogenic, chondrogenic, or adipogenic lineages.